Evidence map›Paper›PMID 32210205›Full record

ArticleSensors (Basel, Switzerland)2020

Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells.

Azarakhsh Oladzad, Maryam Nikkhah, Saman Hosseinkhani

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Identification of NLRP3International journal of molecular sciences · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Azarakhsh OladzadDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran P.O. Box 14115-175, Iran.
Maryam NikkhahDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran P.O. Box 14115-175, Iran.
Saman HosseinkhaniDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran P.O. Box 14115-175, Iran.ORCID 0000-0002-0345-7909
Tarbiat Modares University · IR

Funding

European Commission EPIC 690939
6 · The paper itself

Abstract

The apoptotic protease-activating factor 1 (Apaf-1) split luciferase biosensor has been used as a biological tool for the detection of early stage of apoptosis. The effect of doxorubicin in a cell-based assay and the addition of cytochrome

Indexed as

ApoptosisApoptosomesApoptotic Protease-Activating Factor 1Biosensing TechniquesCaspase 3Cell SurvivalEnzyme ActivationEtoposideHEK293 CellsHumansLuciferasesAPAF1 protein, humanApoptosomesApoptotic Protease-Activating Factor 1Caspase 3EtoposideLuciferasesapoptosisapoptosomeluciferase complementary assay

Identifiers

PMID32210205
PMCPMC7146213
OpenAlexW3012882507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.