ReviewInternational journal of molecular sciences2020
MiRNAs in the Peri-Implantation Period: Contribution to Embryo-Maternal Communication in Pigs.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- MicroRNAs as Regulators of Reproductive Function: From Gametogenesis to Pregnancy.Journal of developmental biology · 2026Review
- Expression of miRNAs Associated With Embryo Development and DNA Damage Response in Porcine Embryos.Molecular reproduction and development · 2025Article
- Dietary inulin supplementation in early gestation regulates uterine fluid exosomes and angiogenesis to improve embryo implantation in sows.Journal of animal science and biotechnology · 2025Article
- Combined metabolome and transcriptome analysis provides molecular insights into reproductive process in Chuanxiang Black and Landrace pigs.Frontiers in genetics · 2025Article
- The Impact of Adenomyosis on Pregnancy.Biomedicines · 2024Review
- Validation of Selected MicroRNA Transcriptome Data in the Bovine Corpus Luteum during Early Pregnancy by RT-qPCR.Current issues in molecular biology · 2024Article
- Effects of Low and High Maternal Protein Intake on Fetal Skeletal Muscle miRNAome in Sheep.Animals : an open access journal from MDPI · 2024Article
- Metabolomics reveals early pregnancy biomarkers in sows: a non-invasive diagnostic approach.Frontiers in veterinary science · 2024Article
- Identifying selection signatures for immune response and resilience to Aleutian disease in mink using genotype data.Frontiers in genetics · 2024Article
- Proteomic profiles and the function of RBP4 in endometrium during embryo implantation phases in pigs.BMC genomics · 2023Article
- Integrated Analysis of DNA Methylation and Gene Expression in Porcine Placental Development.International journal of molecular sciences · 2023Article
- microRNAs as A Biomarker to Predict Embryo Quality Assessment in In Vitro Fertilization.International journal of fertility & sterility · 2023Article
- miR-1246 is implicated as a possible candidate for endometrium remodelling facilitating implantation in buffalo (Bubalus bubalis).Veterinary medicine and science · 2023Article
- Effect of miR-143-3p from Extracellular Vesicles of Porcine Uterine Luminal Fluid on Porcine Trophoblast Cells.Animals : an open access journal from MDPI · 2022Article
- Small Non-Coding RNAs as New Biomarkers to Evaluate the Quality of the Embryo in the IVF Process.Biomolecules · 2022Article
- Oviductal Extracellular Vesicles Enhance Porcine In Vitro Embryo Development by Modulating the Embryonic Transcriptome.Biomolecules · 2022Article
- Male-female communication enhances release of extracellular vesicles leading to high fertility in Drosophila.Communications biology · 2022Article
- Early steps of embryo implantation are regulated by exchange of extracellular vesicles between the embryo and the endometrium.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Article
- Differential MicroRNA Expression in Porcine Endometrium Related to Spontaneous Embryo Loss during Early Pregnancy.International journal of molecular sciences · 2022Article
- Identification of Genomic Regions and Candidate Genes for Litter Traits in French Large White Pigs Using Genome-Wide Association Studies.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
MicroRNAs (miRNAs) constitute a large family of noncoding RNAs, approximately 22 nucleotides long, which function as guide molecules in RNA silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all developmental and pathophysiological processes in animals. To date, the regulatory roles of miRNAs in reproduction, such as fertilization, embryo development, implantation, and placenta formation, among others, have been demonstrated in numerous mammalian species, including domestic livestock such as pigs. Over the past years, it appeared that understanding the functions of miRNAs in mammalian reproduction can substantially improve our understanding of the biological challenges of successful reproductive performance. This review describes the current knowledge on miRNAs, specifically in relation to the peri-implantation period when the majority of embryonic mortality occurs in pigs. To present a broader picture of crucial peri-implantation events, we focus on the role of miRNA-processing machinery and miRNA-mRNA infarctions during the maternal recognition of pregnancy, leading to maintenance of the corpus luteum function and further embryo implantation. Furthermore, we summarize the current knowledge on cell-to-cell communication involving extracellular vesicles at the embryo-maternal interface in pigs. Finally, we discuss the potential of circulating miRNAs to serve as indicators of ongoing embryo-maternal crosstalk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.