Evidence map›Paper›PMID 32210083›Full record

ArticleVaccines2020

Sarah-Kim Friedrich, Rosa Schmitz, Michael Bergerhausen, Judith Lang, Lamin B Cham, Vikas Duhan, Dieter Häussinger, Cornelia Hardt, Marylyn Addo, Marco Prinz and 3 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Microbiology spectrum · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Molecular Signature of Monocytes Shaped by theInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Sarah-Kim FriedrichInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Rosa SchmitzInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Michael BergerhausenInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Judith LangInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.ORCID 0000-0001-5352-106X
Lamin B ChamInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.ORCID 0000-0002-6855-5657
Vikas DuhanInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Dieter HäussingerClinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich-Heine-University, Moorenstrasse 5, 40225 Düsseldorf, Germany.
Cornelia HardtInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
Marylyn AddoDivision of Infectious Diseases, First Department of Medicine, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Marco PrinzInstitute of Neuropathology, Medical Faculty, University of Freiburg, 79106 Freiburg, Germany.
Kenichi AsanoLaboratory of Immune Regulation, School of Life Science, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.ORCID 0000-0002-0218-1517
Philipp Alexander LangDepartment of Molecular Medicine II, Medical Faculty, University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.
Karl Sebastian LangInstitute of Immunology, University of Duisburg-Essen, Hufelandstrasse 55, 45147 Essen, Germany.
University of Duisburg-Essen · DEHeinrich Heine University Düsseldorf · DETokyo University of Pharmacy and Life Sciences · JPUniversität Hamburg · DEUniversity of Freiburg · DE

Funding

Deutsche Forschungsgemeinschaft SFB974
6 · The paper itself

Abstract

Ebola virus epidemics can be effectively limited by the VSV-EBOV vaccine (Ervebo) due to its rapid protection abilities; however, side effects prevent the broad use of VSV-EBOV as vaccine. Mechanisms explaining the efficient immune activation after single injection with the VSV-EBOV vaccine remain mainly unknown. Here, using the clinically available VSV-EBOV vaccine (Ervebo), we show that the cell-intrinsic expression of the interferon-inhibitor

Indexed as

adaptive immunityCD169+ macrophagesEbola virusenforced replicationErveboinnate immunityUsp18vaccinationVSV-EBOV

Identifiers

PMID32210083
PMCPMC7157200
OpenAlexW3012746885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.