Evidence map›Paper›PMID 32210072›Full record

ArticleToxins2020

An Appetite for Destruction: Detecting Prey-Selective Binding of α-Neurotoxins in the Venom of Afro-Asian Elapids.

Richard J Harris, Christina N Zdenek, David Harrich, Nathaniel Frank, Bryan G Fry

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Frontiers in immunology · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Tiny but Mighty:Toxins · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Venom phenotype conservation suggests integrated specialization in a lizard-eating snake.Toxicon : official journal of the International Society on Toxinology · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Richard J HarrisVenom Evolution Lab, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-4412-2275
Christina N ZdenekVenom Evolution Lab, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0002-0385-500X
David HarrichQIMR Berghofer, Royal Brisbane Hospital, Brisbane, QLD 4029, Australia.
Nathaniel FrankMtoxins, 1111 Washington Ave, Oshkosh, WI 54901, USA.
Bryan G FryVenom Evolution Lab, School of Biological Sciences, University of Queensland, St Lucia, QLD 4072, Australia.ORCID 0000-0001-6661-1283
The University of Queensland · AUOshkosh (United States) · USQIMR Berghofer Medical Research Institute · AU

Funding

Australian Research Council DP190100304
6 · The paper itself

Abstract

Prey-selective venoms and toxins have been documented across only a few species of snakes. The lack of research in this area has been due to the absence of suitably flexible testing platforms. In order to test more species for prey specificity of their venom, we used an innovative taxonomically flexible, high-throughput biolayer interferometry approach to ascertain the relative binding of 29 α-neurotoxic venoms from African and Asian elapid representatives (26

Indexed as

AfricaAnimalsAsiaElapidaeElapid VenomsEvolution, MolecularNeurotoxinsPhylogenyPredatory BehaviorProtein BindingReceptors, NicotinicElapid VenomsNeurotoxinsReceptors, Nicotinicalpha-neurotoxinsElapidaeneurotoxicitynicotinic acetylcholine receptorprey specificityvenom

Identifiers

PMID32210072
PMCPMC7150784
OpenAlexW3013462984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.