Evidence map›Paper›PMID 32209961›Full record

ReviewKorean journal of anesthesiology2020

Emergence agitation: current knowledge and unresolved questions.

Seok-Jin Lee, Tae-Yun Sung

3 registry-linked trialsOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Korean journal of anesthesiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 125 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 12 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05903326 completednot on this mapstarted 2022, after this paper: background citation

Dexmedetomidine as a Sole Premedication for BMT Placement in Children Undergoing Bilateral Myringotomy Tube Placement Surgery

TypeobservationalSponsorNemours Children's ClinicRan2022 to 2023Enrolled276ConditionsEffect of Drug, Complication of TreatmentArmsDexmedetomidine
NCT06306040 phase3unknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of Intravenous Nalbuphine Versus Magnesium Sulfate on Emergence Agitation in Pediatric Patients Scheduled for Hypospadias Repair

TypeinterventionalSponsorAssiut UniversityRan2024 to 2025Enrolled105ConditionsEmergence DeliriumArmsNalbuphine Versus Magnesium Sulfate
NCT06543134 recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation

TypeobservationalSponsorKocaeli City HospitalRan2024 to 2024Enrolled120ConditionsHypothermia, Anesthesia, Agitation, Emergence, Postoperative ComplicationsArmssurgery, sedation scale
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 12 syntheses or guidelines pooled it, 214 citations in OpenAlex.

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  5. Dexmedetomidine Mitigates Sevoflurane-Induced Neurodevelopmental Effects in Paediatric Anaesthesia: A Meta-Analysis and Preclinical Study.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Seok-Jin LeeDepartment of Anesthesiology and Pain Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.
Tae-Yun SungDepartment of Anesthesiology and Pain Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea.
Konyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergence agitation (EA), also referred to as emergence delirium, can have clinically significant consequences. The mechanism of EA remains unclear. The proposed risk factors of EA include age, male sex, type of surgery, emergency operation, use of inhalational anesthetics with low blood-gas partition coefficients, long duration of surgery, anticholinergics, premedication with benzodiazepines, voiding urgency, postoperative pain, and the presence of invasive devices. If preoperative or intraoperative objective monitoring could predict the occurrence of agitation during emergence, this would help to reduce its adverse consequences. Several tools are available for assessing EA. However, there are no standardized clinical research practice guidelines and its incidence varies considerably with the assessment tool or definition used. Total intravenous anesthesia, propofol, μ-opioid agonists, N-methyl-D-aspartate receptor antagonists, nefopam, α2-adrenoreceptor agonists, regional analgesia, multimodal analgesia, parent-present induction, and preoperative education for surgery may help in preventing of EA. However, it is difficult to identify patients at high risk and apply preventive measures in various clinical situations. The risk factors and outcomes of preventive strategies vary with the methodologies of studies and patients assessed.This review discusses important outcomes of research on EA and directions for future research.

Indexed as

Anesthetics, InhalationEmergence DeliriumAdultAnesthesia Recovery PeriodChildChild, PreschoolHumansMalePsychomotor AgitationSevofluraneAnesthetics, InhalationSevofluraneAnesthesiaEmergence agitationEmergence deliriumIncidencePractice guidelineRisk

Identifiers

PMID32209961
PMCPMC7714637
OpenAlexW3013973498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.