ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology1988
Time-course of blood acid-base state during arousal from hibernation in the European hamster.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 38 citations in OpenAlex.
- Body Protein Sparing in Hibernators: A Source for Biomedical Innovation.Frontiers in physiology · 2021Review
- White-nose syndrome initiates a cascade of physiologic disturbances in the hibernating bat host.BMC physiology · 2014Article
- State-dependent regulation of cortical blood flow and respiration in hamsters: response to hypercapnia during arousal from hibernation.The Journal of physiology · 2003Article
- Reassessment of the cold-labile nature of phosphofructokinase from a hibernating ground squirrel.Molecular and cellular biochemistry · 2001Article
- Intracellular pH during daily torpor in Peromyscus maniculatus.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 1990Article
- pH-temperature interactions on protein function and hibernation: GDP binding to brown adipose tissue mitochondria.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 1988Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. Arterial blood was sampled at 15 min-intervals in European hamsters Cricetus cricetus fitted with indwelling catheters, from deep hibernation to full arousal. Temperature-corrected pH and PCO2, respectively pH* and P*CO2, were directly measured at 37 degrees C. 2. Deep hibernation corresponded to a respiratory acidosis: pH* = 7.01 +/- 0.01 (mean +/- SE), P*CO2 = 160 +/- 4 Torr (n = 9 animals). 3. Three periods could be distinguished in the arousal: (i) a period of hyperventilation (28 +/- 5 min), in which P*CO2 was reduced to 79 +/- 4 Torr, while cheek pouch temperature increased only by 0.9 +/- 0.2 degrees C; (ii) a period of metabolic acidification by lactate accumulation (84 +/- 6 min), corresponding to the period of peak thermogenesis; (iii) a progressive return to euthermic conditions (104 +/- 10 min), by simultaneous respiratory and metabolic alkalinization. 4. Over 60% of the blood CO2 stores accumulated at the beginning of the hibernation bout were released by hyperventilation during the first period, prior to the full development of thermogenesis. This is in agreement with the hypothesis of an inhibitory role of the respiratory acidosis in hibernation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.