Evidence map›Paper›PMID 32209826›Full record

SynthesisCritical pathways in cardiology2020

Systematic Review of Clinical Decision Support Systems for Prehospital Acute Coronary Syndrome Identification.

Charles Richard Knoery, Janet Heaton, Rob Polson, Raymond Bond, Aleeha Iftikhar, Khaled Rjoob, Victoria McGilligan, Aaron Peace, Stephen James Leslie

Registry-linked trialOpen access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Critical pathways in cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07461415 (CONNECT-HTN Trial - Coaching and Navigation by CHWs Through Telehealth for High-risk Hypertension), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07461415 narecruitingnot on this mapstarted 2026, after this paper: background citation

CONNECT-HTN Trial - Coaching and Navigation by CHWs Through Telehealth for High-risk Hypertension

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2026 to 2029Enrolled3,620ConditionsHypertensionArmsCONNECT-HTN, Standard ED management
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Prediction of acute neurovascular syndromes with prehospital clinical features witnessed by bystanders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Charles Richard KnoeryFrom the Division of Rural Health and Wellbeing, University of the Highlands and Islands, Centre for Health Science, Inverness, United Kingdom.
Janet HeatonFrom the Division of Rural Health and Wellbeing, University of the Highlands and Islands, Centre for Health Science, Inverness, United Kingdom.
Rob PolsonHighland Health Sciences Library, University of the Highlands and Islands, Centre for Health Science, Inverness, United Kingdom.
Raymond BondUlster University, Jordanstown Campus, Newtownabbey, Northern Ireland, United Kingdom.
Aleeha IftikharUlster University, Jordanstown Campus, Newtownabbey, Northern Ireland, United Kingdom.
Khaled RjoobUlster University, Jordanstown Campus, Newtownabbey, Northern Ireland, United Kingdom.
Victoria McGilliganCentre for Personalised Medicine, Ulster University, Londonderry, Northern Ireland, United Kingdom.
Aaron PeaceCentre for Personalised Medicine, Ulster University, Londonderry, Northern Ireland, United Kingdom.
Stephen James LeslieFrom the Division of Rural Health and Wellbeing, University of the Highlands and Islands, Centre for Health Science, Inverness, United Kingdom.
University of Ulster · GBUniversity of the Highlands and Islands · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTimely prehospital diagnosis and treatment of acute coronary syndrome (ACS) are required to achieve optimal outcomes. Clinical decision support systems (CDSS) are platforms designed to integrate multiple data and can aid with management decisions in the prehospital environment. The review aim was to describe the accuracy of CDSS and individual components in the prehospital ACS management.

methodsThis systematic review examined the current literature regarding the accuracy of CDSS for ACS in the prehospital setting, the influence of computer-aided decision-making and of 4 components: electrocardiogram, biomarkers, patient history, and examination findings. The impact of these components on sensitivity, specificity, and positive and negative predictive values was assessed.

resultsA total of 11,439 articles were identified from a search of databases, of which 199 were screened against the eligibility criteria. Eight studies were found to meet the eligibility and quality criteria. There was marked heterogeneity between studies which precluded formal meta-analysis. However, individual components analysis found that patient history led to significant improvement in the sensitivity and negative predictive values. CDSS which incorporated all 4 components tended to show higher sensitivities and negative predictive values. CDSS incorporating computer-aided electrocardiogram diagnosis showed higher specificities and positive predictive values.

conclusionsAlthough heterogeneity precluded meta-analysis, this review emphasizes the potential of ACS CDSS in prehospital environments that incorporate patient history in addition to integration of multiple components. The higher sensitivity of certain components, along with higher specificity of computer-aided decision-making, highlights the opportunity for developing an integrated algorithm with computer-aided decision support.

Indexed as

AlgorithmsElectrocardiographyAcute Coronary SyndromeDecision Support Systems, ClinicalEmergency Medical ServicesHumansPredictive Value of Tests

Identifiers

PMID32209826
PMCPMC7386869
OpenAlexW3013863803

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.