Evidence map›Paper›PMID 32209770›Full record

ArticleNeural regeneration research2020

Offspring of rats with cerebral hypoxia-ischemia manifest cognitive dysfunction in learning and memory abilities.

Lu-Lu Xue, Fang Wang, Rui-Ze Niu, Ya-Xin Tan, Jia Liu, Yuan Jin, Zheng Ma, Zi-Bin Zhang, Ya Jiang, Li Chen and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. ApTOLL ameliorates cognitive dysfunction and brain injury in ischemic stroke by regulating the miR-335-5p/IRAK1 axis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Lu-Lu XueDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province; Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan Province, China.
Fang WangDepartment of Science and Technology, Kunming Medical University, Kunming, Yunnan Province, China.
Rui-Ze NiuDepartment of Laboratory Zoology, Kunming Medical University, Kunming, Yunnan Province, China.
Ya-Xin TanInstitute of Neuroscience, Kunming Medical University, Kunming, Yunnan Province, China.
Jia LiuDepartment of Laboratory Zoology, Kunming Medical University, Kunming, Yunnan Province, China.
Yuan JinInstitute of Neuroscience, Kunming Medical University, Kunming, Yunnan Province, China.
Zheng MaInstitute of Neuroscience, Kunming Medical University, Kunming, Yunnan Province, China.
Zi-Bin ZhangInstitute of Neurological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Ya JiangDepartment of Laboratory Zoology, Kunming Medical University, Kunming, Yunnan Province, China.
Li ChenInstitute of Neurological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Qing-Jie XiaInstitute of Neurological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Jun-Jie ChenSouthwest Medical University, Luzhou, Sichuan Province, China.
Ting-Hua WangInstitute of Neuroscience, Kunming Medical University, Kunming, Yunnan Province; Institute of Neurological Disease, Department of Anesthesiology, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Liu-Lin XiongDepartment of Anesthesiology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou Province, China; School of Pharmacy and Medical Sciences, Division of Health Sciences, University of South Australia, Adelaide, Australia.
Kunming Medical University · CNWest China Hospital of Sichuan University · CNZunyi Medical University · CNSichuan University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal hypoxic-ischemic encephalopathy is a serious neurological disease, often resulting in long-term neurodevelopmental disorders among surviving children. However, whether these neurodevelopmental issues can be passed to offspring remains unclear. The right common carotid artery of 7-day-old parental-generation rats was subjected to permanent ligation using a vessel electrocoagulator. Neonatal hypoxic-ischemic rat models were established by subjecting the rats to 8% O

Indexed as

cerebral atrophycerebral infarctcerebral liquefactioncognitive impairmentmagnetic resonance imagingneonatal brain hypoxia and ischemianeuronal apoptosisoffspring

Identifiers

PMID32209770
PMCPMC7437586
OpenAlexW3008257932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.