Evidence map›Paper›PMID 32209728›Full record

Trial reportAging2020

Efficacy and safety of recombinant human follicle-stimulating hormone in patients undergoing

Linli Hu, Songying Zhang, Song Quan, Jieqiang Lv, Weiping Qian, Yuanhua Huang, Weiying Lu, Yingpu Sun

Erratum issuedOpen access · greenAbstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Linli HuThe First Affiliated Hospital of Zhengzhou University, Reproductive Medicine, Zhengzhou, China.
Songying ZhangSir Run Run Shaw Hospital of Zhejiang University, Reproductive Medicine, Hangzhou, China.
Song QuanSouthern Medical University, Reproductive Medicine, Guangzhou, China.
Jieqiang LvSecond Affiliated Hospital of Wenzhou Medical University, Reproductive Medicine, Wenzhou, China.
Weiping QianPeking University Shenzhen Hospital, Reproductive Medicine, Shenzhen, China.
Yuanhua HuangHainan Medical College, Reproductive Medicine, Haikou, China.
Weiying LuHainan Medical College, Reproductive Medicine, Haikou, China.
Yingpu SunThe First Affiliated Hospital of Zhengzhou University, Reproductive Medicine, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CNHainan Medical College Hospital · CNPeking University Shenzhen Hospital · CNSouthern Medical University · CNWenzhou Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the ovarian responses after administration of two recombinant follicle-stimulating hormone (r-FSH) preparations under gonadotropin-releasing hormone (GnRH) analogue downregulation, we conducted a phase 3, randomized, multicenter, assessor-blind, active-controlled, parallel group study. The primary outcome was the number of oocytes retrieved. The secondary outcomes included total dose and duration of r-FSH administered, oocyte quality, blood estradiol levels, follicular development, fertilization rates, implantation rates, and pregnancy rates (biochemical, clinical, and ongoing). A total of 451 patients with infertility were randomized to receive either Follitrope™ Prefilled Syringe or Gonal-F

Indexed as

AdultEmbryo TransferFemaleFertilization in VitroFollicle Stimulating HormoneFollicle Stimulating Hormone, HumanGonadotropin-Releasing HormoneHumansOocyte RetrievalPregnancyPregnancy RateRecombinant ProteinsTreatment OutcomeYoung AdultFollicle Stimulating HormoneFollicle Stimulating Hormone, Humanfollitropin alfafollitropin betaGonadotropin-Releasing HormoneRecombinant Proteinsassisted reproductive technology (ART)oocytes retrieved, IVF-ETovarian stimulationrecombinant human FSH (r-hFSH)

Identifiers

PMID32209728
PMCPMC7138541
OpenAlexW3013330313

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.