Evidence map›Paper›PMID 32209680›Full record

ArticlemBio2020

Characterization of the Efflux Capability and Substrate Specificity of Aspergillus fumigatus PDR5-like ABC Transporters Expressed in Saccharomyces cerevisiae.

Brooke D Esquivel, Jeffrey M Rybak, Katherine S Barker, Jarrod R Fortwendel, P David Rogers, Theodore C White

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Understanding multi-azole resistance inFrontiers in fungal biology · 2026
    Article
  3. Article
  4. Multidrug efflux pumps and innate azole resistance of Mucor lusitanicus.The Journal of antimicrobial chemotherapy · 2025
    Article
  5. Genome-Wide Identification ofInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Exploration of Response Mechanisms in the Gills of Pacific Oyster (Animals : an open access journal from MDPI · 2024
    Article
  8. Article
  9. The Transcriptome Response to Azole Compounds inJournal of fungi (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Transport across Membranes: Techniques for Measuring Efflux in Fungal Cells.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Identification of Promising Antifungal Drugs againstJournal of fungi (Basel, Switzerland) · 2021
    Article
  16. Studies in mycology · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. PDR TransporterFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brooke D EsquivelDivision of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, USA.ORCID 0000-0001-7328-4057
Jeffrey M RybakDepartment of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Katherine S BarkerDepartment of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Jarrod R FortwendelDepartment of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
P David RogersDepartment of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Theodore C WhiteDivision of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, USA whitetc@umkc.edu.
University of Tennessee Health Science Center · USUniversity of Missouri–Kansas City · US

Funding

Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8M
Non-cyp51A-mutation Mediated Triazole Resistance in Aspergillus fumigatusR01AI143197 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI FORTWENDEL, JARROD R., ROGERS, P. DAVID · 2020 to 2024
$3.3M
Fungal Ras-mediated invasive growth mechanismsR01AI106925 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI FORTWENDEL, JARROD R. · 2014 to 2018
$1.5M
NIAID NIH HHS R01 AI058145NIAID NIH HHS R01 AI106925NIAID NIH HHS R01 AI143197
6 · The paper itself

Abstract

This research analyzed six

Indexed as

Antifungal AgentsAspergillus fumigatusATP-Binding Cassette TransportersFungal ProteinsGene DeletionMicrobial Sensitivity TestsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSubstrate SpecificityAntifungal AgentsATP-Binding Cassette TransportersFungal ProteinsPDR5 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsABC transporterAspergillus fumigatusdrug resistanceeffluxefflux inhibitorfilamentous fungiPDR5

Identifiers

PMID32209680
PMCPMC7157516
OpenAlexW3013883065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.