Evidence map›Paper›PMID 32209658›Full record

ArticleThe Journal of biological chemistry2020

Chemical roadblocking of DNA transcription for nascent RNA display.

Eric J Strobel, John T Lis, Julius B Lucks

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Eric J StrobelDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208 eric.strobel@northwestern.edu ejs294@cornell.edu.ORCID 0000-0002-7082-2881
John T LisDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14850.ORCID 0000-0003-1201-9406
Julius B LucksDepartment of Chemical and Biological Engineering, Northwestern University, Evanston, Illinois 60208.ORCID 0000-0002-0619-6505
Northwestern University · USCornell University · US

Funding

COORDINATE GENE REGULATION IN ANIMAL CELLSR01GM025232 · NIGMS · CORNELL UNIVERSITY ITHACA · PI LIS, JOHN T · 1985 to 2020
$8.4M
COORDINATE GENE REGULATION IN ANIMAL CELLSR37GM025232 · NIGMS · CORNELL UNIVERSITY ITHACA · PI LIS, JOHN THOMAS · 1995 to 2004
$2.5M
NIGMS NIH HHS R01 GM025232NIGMS NIH HHS R37 GM025232
6 · The paper itself

Abstract

Site-specific arrest of RNA polymerases (RNAPs) is fundamental to several technologies that assess RNA structure and function. Current

Indexed as

RNATranscription, GeneticDNADNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsTemplates, GeneticDNADNA-Directed RNA PolymerasesEscherichia coli ProteinsRNAbiotindesthiobiotinetheno-dARNARNA foldingRNA polymeraseRNAP roadblockingsite-specific transcription arresttranscriptiontranslesion synthesis

Identifiers

PMID32209658
PMCPMC7212663
OpenAlexW3013090045

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.