Evidence map›Paper›PMID 32209643›Full record

ArticleBMJ open respiratory research2020

Maintaining quality of life in patients with chronic obstructive pulmonary disease (COPD) by extending the maintenance phase of community-based pulmonary rehabilitation: protocol for a randomised controlled trial (ComEx3 Study).

Derrick Lopez, Nola Cecins, Joanne Cockram, Anna Collins, Holly Landers, Frank Sanfilippo, Tom Briffa, Fraser Brims, Elizabeth Geelhoed, Kevin Murray and 3 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Derrick LopezSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia derrick.lopez@uwa.edu.au.ORCID http://orcid.org/0000-0003-0677-0420
Nola CecinsPhysiotherapy Department, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.
Joanne CockramCommunity Physiotherapy Services, Perth, Western Australia, Australia.
Anna CollinsCommunity Physiotherapy Services, Perth, Western Australia, Australia.
Holly LandersSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Frank SanfilippoSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Tom BriffaSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Fraser BrimsSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Elizabeth GeelhoedSchool of Allied Health, The University of Western Australia, Perth, Western Australia, Australia.
Kevin MurraySchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Kirsten PhillipsLung Foundation Australia, Brisbane, Queensland, Australia.
David PreenSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.
Susan JenkinsSchool of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPulmonary rehabilitation is a core component of the treatment of people with chronic obstructive pulmonary disease (COPD); however, the benefits gained diminish in the ensuing months. The optimal strategy for maintaining the benefits is unclear with weekly supervised maintenance exercise programmes proposed as one strategy. However, the long-term future of maintenance programs is dependent on quality evidence. METHODS AND ANALYSIS: The ComEx3 randomised controlled trial will investigate the efficacy of extending a weekly supervised maintenance programme for an additional 6 months following an initial 10-week maintenance programme (intervention) by comparing with a control group who receive the same 10-week maintenance programme followed by 6 months of usual care. 120 participants with COPD will be recruited. Primary objective is to determine health-related quality of life over 12 months. Secondary objectives are to determine functional exercise capacity trajectory and to perform an economic evaluation of the intervention to the health system. Outcomes will be analysed for superiority according to intention-to-treat and per-protocol approaches. ETHICS AND DISSEMINATION: Approval has been received from the relevant ethics committees. Findings will be disseminated in peer-reviewed journals and conferences, targeting those involved in managing people with COPD as well as those who develop policies and guidelines. CLINICAL

trial registrationANZCTR 12618000933257.

Indexed as

ExerciseQuality of LifeCost-Benefit AnalysisExercise TherapyFollow-Up StudiesForced Expiratory VolumeHealth StatusHumansPulmonary Disease, Chronic ObstructiveSingle-Blind MethodVital Capacityexercisehealth economistpulmonary rehabilitation

Identifiers

PMID32209643
PMCPMC7206909

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.