Evidence map›Paper›PMID 32209511›Full record

ArticleDiagnostic and interventional radiology (Ankara, Turkey)2020

Volumetric MRI-guided, high-intensity focused ultrasound ablation of uterine leiomyomas: ASEAN preliminary experience.

Bilgin Keserci, Nguyen Minh Duc, Chandran Nadarajan, Huynh Quang Huy, Aishah Saizan, Wan Aireene Wan Ahmed, Khalid Osman, Mohd Shafie Abdullah

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Diagnostic and interventional radiology (Ankara, Turkey), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bilgin KeserciDepartment of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia;Department of Radiology, Hospital Universiti Sains Malaysia, USM 16150 Kubang Kerian, Kelantan, Malaysia.
Nguyen Minh DucDepartment of Radiology, Pham Ngoc Thach University School of Medicine, Ho Chi Minh City, Vietnam.
Chandran NadarajanDepartment of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia;Department of Radiology, Hospital Universiti Sains Malaysia, USM 16150 Kubang Kerian, Kelantan, Malaysia.
Huynh Quang HuyDepartment of Radiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
Aishah SaizanDepartment of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia;Department of Radiology, Hospital Universiti Sains Malaysia, USM 16150 Kubang Kerian, Kelantan, Malaysia.
Wan Aireene Wan AhmedDepartment of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia;Department of Radiology, Hospital Universiti Sains Malaysia, USM 16150 Kubang Kerian, Kelantan, Malaysia.
Khalid OsmanDepartment of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia;Department of Radiology, Hospital Universiti Sains Malaysia, USM 16150 Kubang Kerian, Kelantan, Malaysia.
Mohd Shafie AbdullahDepartment of Radiology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia;Department of Radiology, Hospital Universiti Sains Malaysia, USM 16150 Kubang Kerian, Kelantan, Malaysia.
Ho Chi Minh City Medicine and Pharmacy University · VNPham Ngoc Thach University of Medicine · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe sought to present our preliminary experience on the effectiveness and safety of magnetic resonance imaging (MRI)-guided, high-intensity focused ultrasound (HIFU) therapy using a volumetric ablation technique in the treatment of Association of Asian Nations (ASEAN) patients with symptomatic uterine leiomyomas.

methodsThis study included 33 women who underwent HIFU treatment. Tissue characteristics of leiomyomas were assessed based on T2- and T1-weighted MRI. The immediate nonperfused volume (NPV) ratio and the treatment effectiveness of MRI-guided HIFU on the basis of the degrees of volume reduction and improvement in transformed symptom severity score (SSS) were assessed.

resultsThe median immediate NPV ratio was 89.8%. Additionally, the median acoustic sonication power and HIFU treatment durations were 150 W and 125 min, respectively. At six-month follow-up, the median leiomyoma volume had decreased from 139 mL at baseline to 84 mL and the median transformed SSS had decreased from 56.2 at baseline to 18.8. No major adverse events were observed.

conclusionThe preliminary results demonstrated that volumetric MRI-guided HIFU therapy for the treatment of symptomatic leiomyomas in ASEAN patients appears to be clinically acceptable with regard to treatment effectiveness and safety.

Indexed as

AdultAftercareAsiaFemaleHigh-Intensity Focused Ultrasound AblationHumansLeiomyomaMagnetic Resonance ImagingMagnetic Resonance Imaging, InterventionalMiddle AgedRetrospective StudiesSafetySeverity of Illness IndexTreatment OutcomeUterine Neoplasms

Identifiers

PMID32209511
PMCPMC7239360
OpenAlexW3012096479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.