Evidence map›Paper›PMID 32209175›Full record

ArticleBiomedical and environmental sciences : BES2020

Comparative Ligandomic Analysis of Human Lung Epithelial Cells Exposed to PM

Hong Tian, Akhalesh Shakya, Feng Wang, Wei Dong Wu, Wei Li

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical and environmental sciences : BES, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hong TianSchool of Public Health, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Akhalesh ShakyaBascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Miami 33136, Florida, USA.
Feng WangDepartment of Genomic Medicine, UT MD Anderson Cancer Center, Houston 77054, TX, USA.
Wei Dong WuSchool of Public Health, Xinxiang Medical University, Xinxiang 453003, Henan, China.
Wei LiBascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, Miami 33136, Florida, USA.
University of Miami · USXinxiang Medical University · CN

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Dmitry V Ivanov · 2004 to 2026
$12.2M
A selective angiogenesis blocker to treat retinopathy of prematurityR24EY028764 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LI, WEI · 2019 to 2023
$7.6M
A Diabetic Retinopathy-Associated Vascular Permeability FactorR01EY027749 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LI, WEI · 2018 to 2022
$2.2M
A disease-specific retinal angiogenic factor and its receptorR21EY027065 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LI, WEI · 2016 to 2017
$422k
Developing a novel therapy for diabetic retinopathyR41EY027665 · NEI · EVERGLADES BIOPHARMA, LLC · PI LI, WEI, TIAN, HONG · 2017 to 2017
$225k
NEI NIH HHS P30 EY014801NEI NIH HHS R01 EY027749NEI NIH HHS R21 EY027065NEI NIH HHS R24 EY028764NEI NIH HHS R41 EY027665
6 · The paper itself

Abstract

objectiveTo investigate whether exposure to particulate matter of diameter equal to or less than 2.5 μm (PM

methodsHuman A549 lung epithelial cells (LECs) were treated with or without PM

resultsWe found 143 ligands with increased binding to PM

conclusionThese results suggest that the newly-developed ligandomics is a valuable approach to globally profile the response of LECs to PM

Indexed as

A549 CellsAir PollutantsHumansLigandsParticle SizeParticulate MatterAir PollutantsLigandsParticulate MatterComparative ligandomicsLigandLigandomicsLung epithelial cellPM2.5

Identifiers

PMID32209175
PMCPMC7607556
OpenAlexW3013707929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.