ArticleBMC microbiology2020
The effects of daily fasting hours on shaping gut microbiota in mice.
Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04674176 (The Potential Weight Loss Benefits of Rifaximin in an Intermittent Fasting Diet), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Potential Weight Loss Benefits of Rifaximin in an Intermittent Fasting Diet
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The effects of time-restricted eating and Ramadan fasting on gut microbiota composition: a systematic review of human and animal studies.Nutrition reviews · 2024Pooled it
- Yak Gut Microbiota: A Systematic Review and Meta-Analysis.Frontiers in veterinary science · 2022Pooled it
- Randomized trial of the effect of esomeprazole on functional dyspepsia during Ramadan fasting.Scientific reports · 2025Trial
- Circadian synchronization between diet and gut microbiota in modulating host's health.Gut microbes · 2026Review
- Stage-Specific Dynamic of Gut Microbiota Across the Musk-Secretion Cycle in Forest Musk Deer (Microorganisms · 2026Article
- Intermittent Fasting and the Gut Microbiota: Mechanisms Linking Microbial Remodeling to Metabolic and Immune Regulation.Nutrients · 2026Review
- Fasting primes small intestinal regeneration after damage via a microbiome-metabolite-chromatin axis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Shaped by Fire: Unravelling the Impact of Fire on Lizard Gut Microbiome.Molecular ecology · 2026Article
- Navigating the duality of Akkermansia muciniphila.Nature microbiology · 2026Review
- Intermittent Fasting and Probiotics for Gut Microbiota Modulation in Type 2 Diabetes Mellitus: A Narrative Review.Nutrients · 2025Review
- Article
- Intermittent fasting and metabolic dysfunction-associated steatotic liver disease: the potential role of the gut-liver axis.Cell & bioscience · 2025Review
- Gut microbiota diversity in obese rats treated with intermittent fasting, probiotic-fermented camel milk with or without dates and their combinations.Scientific reports · 2025Article
- Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling.iScience · 2025Article
- Dietary composition and fasting regimens differentially impact the gut microbiome and short-chain fatty acid profile in a Pakistani cohort.Frontiers in systems biology · 2025Article
- Mechanisms of time-restricted feeding-induced neuroprotection and neuronal plasticity in ischemic stroke as a function of circadian rhythm.Experimental neurology · 2025Review
- Time-restricted eating as a potential strategy for healthy lifespan: an evaluation of current evidence.Frontiers in medicine · 2025Review
- The potential of olfaction loss to induce cognitive impairment and anxiety behavior in mice via the microbiota-gut-brain axis.Frontiers in microbiology · 2025Article
- Article
- Hematological, biochemical, and histopathological evaluation of theOpen veterinary journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundIt has recently been reported that intermittent fasting shapes the gut microbiota to benefit health, but this effect may be influenced to the exact fasting protocols. The purpose of this study was to assess the effects of different daily fasting hours on shaping the gut microbiota in mice. Healthy C57BL/6 J male mice were subjected to 12, 16 or 20 h fasting per day for 1 month, and then fed ad libitum for an extended month. Gut microbiota was analyzed by 16S rRNA gene-based sequencing and food intake was recorded as well.
resultsWe found that cumulative food intake was not changed in the group with 12 h daily fasting, but significantly decreased in the 16 and 20 h fasting groups. The composition of gut microbiota was altered by all these types of intermittent fasting. At genus level, 16 h fasting led to increased level of Akkermansia and decreased level of Alistipes, but these effects disappeared after the cessation of fasting. No taxonomic differences were identified in the other two groups.
conclusionsThese data indicated that intermittent fasting shapes gut microbiota in healthy mice, and the length of daily fasting interval may influence the outcome of intermittent fasting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.