ArticleBioanalysis2020
A novel, robust method for quantification of multiple kynurenine pathway metabolites in the cerebrospinal fluid.
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In one paragraph
Article in Bioanalysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 39 citations in OpenAlex.
- Intravenous administration of LPS activates the kynurenine pathway in healthy male human subjects: a prospective placebo-controlled cross-over trial.Journal of neuroinflammation · 2021Trial
- Repetitive tooth-clenching triggers kynurenine pathway activation in masseter muscle of women with temporomandibular disorders myalgia.Pain reports · 2026Article
- Significance of NAD anabolism profiles in neurological diseases.Metabolic brain disease · 2026Review
- The kynurenine pathway in depression and schizophrenia: convergent signals, divergent states, and clinical signatures.EXCLI journal · 2026Review
- Neuropsychiatric- and cognitive post-acute sequelae of SARS-CoV-2 infection - evidence from K18-hACE C57BL/6 J mice.The international journal of neuropsychopharmacology · 2025Article
- Sensitive Detection of Kynurenic Acid from Biological Fluids Using a Flexible Electrochemical Platform Based on Gold Nanoparticles and Reduced Graphene Oxide.International journal of molecular sciences · 2025Article
- Identification and functional validation of kynureninases from oral bacteria.Journal of oral microbiology · 2025Article
- Neuroactive Kynurenines as Pharmacological Targets: New Experimental Tools and Exciting Therapeutic Opportunities.Pharmacological reviews · 2024Review
- Review
- A Novel RP-UHPLC-MS/MS Approach for the Determination of Tryptophan Metabolites Derivatized with 2-Bromo-4'-Nitroacetophenone.Biomedicines · 2024Article
- Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens.Metabolites · 2024Review
- UPLC-MS/MS method for quantitative determination of the advanced glycation endproductsAnalytical methods : advancing methods and applications · 2023Article
- Article
- Dual administration of lipopolysaccharide induces behavioural changes in rats relevant to psychotic disorders.Acta neuropsychiatrica · 2023Article
- Charting the Next Road Map for CSF Biomarkers in Alzheimer's Disease and Related Dementias.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Brain Kynurenine Pathway Metabolite Levels May Reflect Extent of Neuroinflammation in ALS, FTD and Early Onset AD.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Measurement of kynurenine pathway metabolites by tandem mass spectrometry.Journal of mass spectrometry and advances in the clinical lab · 2023Article
- Article
- NAD+ Biosynthesis Impairment and Acute Kidney Injury after Major Vascular Surgery.Antioxidants (Basel, Switzerland) · 2023Article
- A liquid chromatography-tandem mass spectrometry based method for the quantification of adenosine nucleotides and NAD precursors and products in various biological samples.Frontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 3 countries.
Lilly SchwielerDepartment of Physiology & Pharmacology, Karolinska Institutet, Stockholm 17165, Sweden.
Ada TrepciDepartment of Physiology & Pharmacology, Karolinska Institutet, Stockholm 17165, Sweden.
Stanislaw KrzyzanowskiCenter for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
Sigurd HermanssonWaters Sverige AB, Stockholm 17165, Sweden.
Mathias GranqvistUnit of Neuroimmunology, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm 171 77, Sweden.
Fredrik PiehlUnit of Neuroimmunology, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm 171 77, Sweden.
Tomas VenckunasInstitute of Sport Science & Innovations, Lithuanian Sports University, Kaunas 44221, Lithuania.
Marius BrazaitisInstitute of Sport Science & Innovations, Lithuanian Sports University, Kaunas 44221, Lithuania.
Sigitas KamandulisInstitute of Sport Science & Innovations, Lithuanian Sports University, Kaunas 44221, Lithuania.
Daniel LindqvistDepartment of Clinical Sciences Lund, Faculty of Medicine, Lund University, Psychiatry, Lund 221 84, Sweden.
Arthur Daniel JonesDepartment of Biochemistry & Molecular Biology & Department of Chemistry & Director, RTSF/MSU Mass Spectrometry & Metabolomics Core, Michigan State University, East Lansing, MI 48824, USA.
Sophie ErhardtDepartment of Physiology & Pharmacology, Karolinska Institutet, Stockholm 17165, Sweden.
Lena BrundinDepartment of Physiology & Pharmacology, Karolinska Institutet, Stockholm 17165, Sweden.
Karolinska Institutet · SELithuanian Sports University · LTVan Andel Institute · USKarolinska University Hospital · SELund University · SEMichigan State University · USWSP Sverige (Sweden) · SE
Funding
Inflammatory factors and kynurenine metabolites tracking suicidal behaviorR01MH118211 · NIMH · VAN ANDEL RESEARCH INSTITUTE · PI ACHTYES, ERIC DANIEL, BRUNDIN, LENA CECILIA · 2019 to 2023
$3.7MRole of Kynurenine Pathway Metabolites in Perinatal Depression and SuicidalityR01MH104622 · NIMH · VAN ANDEL RESEARCH INSTITUTE · PI BRUNDIN, LENA CECILIA · 2014 to 2016
$1.2MNIMH NIH HHS R01 MH104622NIMH NIH HHS R01 MH118211
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultCase-Control StudiesChromatography, LiquidCohort StudiesFemaleHumansKynurenineMaleMental DisordersMiddle AgedMultiple SclerosisPicolinic AcidsQuinolinic AcidSuicide, AttemptedTandem Mass SpectrometryTryptophanKynureninepicolinic acidPicolinic AcidsQuinolinic AcidTryptophanLC–MS/MSnicotinic acidpicolinic acidquinolinic acidsuicidetryptophan-kynurenine pathway
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.