Evidence map›Paper›PMID 32209023›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2020

Rats are protected from the stress of chronic pressure overload compared with mice.

Koichi Nishimura, Marko Oydanich, Jie Zhang, Denis Babici, Diego Fraidenraich, Dorothy E Vatner, Stephen F Vatner

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Koichi NishimuraDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Marko OydanichDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Jie ZhangDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Denis BabiciDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Diego FraidenraichDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Dorothy E VatnerDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Stephen F VatnerDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.ORCID 0000-0003-0521-8634
Rutgers, The State University of New Jersey · US

Funding

New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
Skeletal Muscle Basis for Improved Exercise Endurance in RGS14 KOR01HL106511 · NHLBI · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI VATNER, STEPHEN F · 2011 to 2019
$3.8M
Intrinsic Vascular Smooth Muscle Cell StiffnessR01HL102472 · NHLBI · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI VATNER, STEPHEN F · 2010 to 2016
$2.5M
RGS 14 Disruption, Vascular Effects Leading to CardioprotectionR01HL124282 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, STEPHEN F · 2015 to 2018
$2.4M
Angiogenesis Protection Induced by sFRP3 Myocyte/Vascular Cross-TalkR01HL137405 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, DOROTHY EILEEN, VATNER, STEPHEN F · 2017 to 2020
$2.2M
Skeletal Muscle and Brown Adipose Mechanisms Mediating Cardiovascular Risk Factor Protection in RGS14 KOR01HL137368 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, STEPHEN F · 2017 to 2020
$2.1M
SFRP2, cell survival, and coronary vascular angiogenesisR01HL119464 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, DOROTHY EILEEN · 2013 to 2016
$1.8M
Vascular Protection in Hibernating WoodchucksR01HL130848 · NHLBI · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, STEPHEN F · 2016 to 2019
$1.8M
Vevo 3100 High Resolution Imaging SystemS10OD025238 · OD · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, STEPHEN F · 2018 to 2018
$459k
INHIBITION OF ADENYLYL CYCLASE TYPE 5: HEALTHFUL AGING PROTECTIONR21AG053514 · NIA · RBHS-NEW JERSEY MEDICAL SCHOOL · PI VATNER, DOROTHY EILEEN · 2016 to 2017
$437k
NCATS NIH HHS UL1 TR003017NHLBI NIH HHS R01 HL102472NHLBI NIH HHS R01 HL106511NHLBI NIH HHS R01 HL119464NHLBI NIH HHS R01 HL124282NHLBI NIH HHS R01 HL130848NHLBI NIH HHS R01 HL137368NHLBI NIH HHS R01 HL137405NIA NIH HHS R21 AG053514NIH HHS S10 OD025238
6 · The paper itself

Abstract

The goal of this investigation was to compare the effects of chronic (4 wk) transverse aortic constriction (TAC) in Sprague-Dawley rats and C57BL/6J mice. TAC, after 1 day, induced similar left ventricular (LV) pressure gradients in both rats (

Indexed as

Ventricular Function, LeftVentricular PressureVentricular RemodelingAnimalsAortaCapillariesCoronary CirculationDisease Models, AnimalHypertrophy, Left VentricularKi-67 AntigenLigationMice, Inbred C57BLMuscle DevelopmentMyocytes, CardiacNeovascularization, PhysiologicProto-Oncogene Proteins c-kitKi-67 AntigenProto-Oncogene Proteins c-kitTroponin Iangiogenesiscardiac functionheart failurepressure overload

Identifiers

PMID32209023
PMCPMC7272766
OpenAlexW3013291069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.