Evidence map›Paper›PMID 32208832›Full record

ArticleJournal of the American Heart Association2020

Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice.

Peng Wu, Zhong-Xiuzi Gao, Dan-Dan Zhang, Xin-Peng Duan, Andrew S Terker, Dao-Hong Lin, David H Ellison, Wen-Hui Wang

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Mechanistic target of rapamycin complex-1 plays a role in inhibiting kidney KAmerican journal of physiology. Renal physiology · 2026
    Article
  3. Plants (Basel, Switzerland) · 2026
    Article
  4. Mechanistic target of rapamycin complex-2 mediates the effect of overnight high KAmerican journal of physiology. Renal physiology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. SARS-CoV-2 N protein induces hypokalemia in acute kidney injury mice via ENaC-dependent mechanism.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Angiotensin II-Type-1a Receptor and Renal K + Wasting during Overnight Low-Na + Intake.Journal of the American Society of Nephrology : JASN · 2024
    Article
  14. mTORc2 in Distal Convoluted Tubule and Renal K + Excretion during High Dietary K + Intake.Journal of the American Society of Nephrology : JASN · 2024
    Article
  15. Role of calcineurin in regulating renal potassium (KActa physiologica (Oxford, England) · 2024
    Review
  16. Epithelial NaComprehensive Physiology · 2024
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Peng WuInstitute of Hypertension and Kidney Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Zhong-Xiuzi GaoInstitute of Hypertension and Kidney Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Dan-Dan ZhangDepartment of Pharmacology New York Medical College Valhalla NY.
Xin-Peng DuanDepartment of Pharmacology New York Medical College Valhalla NY.
Andrew S TerkerDepartment of Medicine Oregon Health & Science University VA Portland Health Care System Portland OR.
Dao-Hong LinDepartment of Pharmacology New York Medical College Valhalla NY.
David H EllisonDepartment of Medicine Oregon Health & Science University VA Portland Health Care System Portland OR.
Wen-Hui WangDepartment of Pharmacology New York Medical College Valhalla NY.
New York Medical College · USFirst Affiliated Hospital of Zhengzhou University · CNOregon Health & Science University · US

Funding

WNK Kinase Regulation of Thiazide-sensitive NaCl TransportR01DK051496 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI David Hoadley Ellison, CHAO-LING YANG · 1998 to 2026
$8.4M
Role of Kir4.1 in Regulating NCC and ROMK in DCTR01DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2001 to 2020
$7.4M
Kir5.1 regulates Kir4.1 ubiquitination by Nedd4-2 in DCTR01DK115366 · NIDDK · NEW YORK MEDICAL COLLEGE · PI LIN, DAO-HONG · 2018 to 2021
$1.5M
Role of Kir4.1 in Regulating NCC and ROMK in DCTR56DK054983 · NIDDK · NEW YORK MEDICAL COLLEGE · PI ELLISON, DAVID H, WANG, WENHUI · 2021 to 2021
$100k
BLRD VA I01 BX002228NIDDK NIH HHS R01 DK051496NIDDK NIH HHS R01 DK054983NIDDK NIH HHS R01 DK115366NIDDK NIH HHS R56 DK054983
6 · The paper itself

Abstract

Background Angiotensin II stimulates epithelial Na

Indexed as

Angiotensin IIAnimalsEpithelial Sodium ChannelsHyperkalemiaKidney Tubules, CollectingKidney Tubules, DistalMembrane PotentialsMice, KnockoutNatriuresisPotassiumReceptor, Angiotensin, Type 1Receptors, MineralocorticoidRenal EliminationAngiotensin IIEpithelial Sodium ChannelsNr3c2 protein, mousePotassiumReceptor, Angiotensin, Type 1Receptors, MineralocorticoidaldosteroneAT1Rhyperkalemiahypertension

Identifiers

PMID32208832
PMCPMC7428622
OpenAlexW3013171246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.