Evidence map›Paper›PMID 32208712›Full record

ArticleNano letters2020

Tracking Longitudinal Rotation of Silicon Nanowires for Biointerfaces.

Youjin V Lee, David Wu, Yun Fang, Yuxing Peng, Bozhi Tian

Abstract read
In one paragraph

Article in Nano letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Youjin V LeeDepartment of Chemistry, University of Chicago, Chicago, Illinois 60637, United States.
David WuDepartment of Medicine, Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois 60637, United States.
Yun FangDepartment of Medicine, Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois 60637, United States.
Yuxing PengResearch Computing Center, University of Chicago, Chicago, Illinois 60637, United States.
Bozhi TianDepartment of Chemistry, University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0003-0593-0023

Funding

Silicon-based Injectable Micro-gels for Non-genetic and Wireless Modulation of Neurons, Cardiomyocytes and Neuromuscular SystemDP2NS101488 · NINDS · UNIVERSITY OF CHICAGO · PI TIAN, BOZHI · 2016 to 2016
$2.4M
Coronary artery disease locus 1p32.2 and miR92a-PPAP2B signaling in endothelial mechanobiologyR01HL136765 · NHLBI · UNIVERSITY OF CHICAGO · PI FANG, YUN · 2017 to 2021
$2.0M
Spatial Delivery of MicroRNA Inhibitor via Targeted Polyelectrolyte Complex Micelles to Treat Atherosclerosis.R01HL138223 · NHLBI · UNIVERSITY OF CHICAGO · PI FANG, YUN · 2017 to 2021
$2.0M
Regulation of vascular metabolism in acute lung injuryK99HL145113 · NHLBI · UNIVERSITY OF CHICAGO · PI WU, DAVID D · 2019 to 2020
$320k
Mechanical regulation of vascular metabolismF32HL134288 · NHLBI · UNIVERSITY OF CHICAGO · PI WU, DAVID D · 2016 to 2016
$64k
NHLBI NIH HHS F32 HL134288NHLBI NIH HHS K99 HL145113NHLBI NIH HHS R01 HL136765NHLBI NIH HHS R01 HL138223NINDS NIH HHS DP2 NS101488
6 · The paper itself

Abstract

The rolling motion (i.e., longitudinal rotation) of nanomaterials may serve as a proxy to probe microscopic environments. Furthermore, nanoscale rotations in biological systems are common but difficult to measure. Here, we report a new tool that measures rolling motion of a nanowire with a short arm grown at one end. We present a particle detection algorithm with subpixel resolution and image segmentation with principal component analysis that enables precise and automated determination of the nanowire orientation. We show that the nanowires' rolling dynamics can be significantly affected by their surroundings and demonstrate the probes' ability to reflect different nanobio interactions. A non-cell-interacting nanowire undergoes rapid subdiffusive rotation, while a cell-interacting nanowire exhibits superdiffusive unidirectional rotation when the cell membrane actively interacts with the nanowire and slow subdiffusive rotation when it is fully encompassed by the cell. Our method can be used to yield insights into various biophysical and assembly processes.

Indexed as

NanostructuresNanowiresSiliconMotionSiliconBiointerfaceimaginglongitudinal rotationnanowire

Identifiers

PMID32208712
PMCPMC7227009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.