Evidence map›Paper›PMID 32208419›Full record

ArticlePLoS neglected tropical diseases2020

ZIKA Virus infection in pregnant women in French Guiana: More precarious-more at risk.

Edouard Hallet, Claude Flamand, Dominique Rousset, Timothée Bonifay, Camille Fritzell, Séverine Matheus, Maryvonne Dueymes, Balthazar Ntab, Mathieu Nacher

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Spatiotemporal Modeling ofPathogens (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Edouard HalletDFR Santé, Université de Guyane, French Guiana.
Claude FlamandEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Dominique RoussetArbovirus National Reference Center, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Timothée BonifayDFR Santé, Université de Guyane, French Guiana.
Camille FritzellEpidemiology unit, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Séverine MatheusArbovirus National Reference Center, Institut Pasteur in French Guiana, Cayenne, French Guiana.
Maryvonne DueymesLaboratory, Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana.
Balthazar NtabMedical information Department, Centre Hospitalier de l'Ouest Guyanais, Saint-Laurent du Maroni, French Guiana.
Mathieu NacherDFR Santé, Université de Guyane, French Guiana.ORCID 0000-0001-9397-3204
Centre Hospitalier Andrée Rosemon · GFInstitut Pasteur de la Guyane · GFUniversity of French Guiana · GFInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA recent study in French Guiana suggested that populations living in precarious neighborhoods were more at risk for Chikungunya CHIKV than those living in more privileged areas. The objective of the present study was to test the hypothesis that Zika virus (ZIKV) infection was more frequent in precarious pregnant women than in non-precarious pregnant women, as reflected by their health insurance status.

methodsA multicentric cross-sectional study was conducted in Cayenne hospital including ZIKV pregnant women with serological or molecular proof of ZIKV during their pregnancy between January and December 2016. Health insurance information was recorded at delivery, which allowed separating women in: undocumented foreigners, precarious but with residence permit, and non-precarious.

resultsA total of 6654 women were included. Among them 1509 (22,7%) had confirmed ZIKV infection. Most women were precarious (2275/3439) but the proportion of precarious women was significantly greater in ZIKV-confirmed 728/906 (80.4%) than the ZIKV-negatives 1747/2533 (69.0%), p<0.0001. There were 1142 women classified as non-precarious, 1671 were precarious legal residents, and 1435 were precarious and undocumented. Precariousness and undocumented status were associated with a higher prevalence of ZIKV during pregnancy (adjusted prevalence ratio = 1.59 (95%CI = 1.29-1.97), p<0.0001), (adjusted prevalence ratio = 1.5 (95%CI = 1.2-1.8), p<0.0001), respectively.

conclusionsThese results illustrate that in French Guiana ZIKV transmission disproportionately affected the socially vulnerable pregnant women, presumably because of poorer housing conditions, and lack of vector control measures in poor neighborhoods.

Indexed as

Socioeconomic FactorsAdolescentAdultChildCross-Sectional StudiesFemaleFrench GuianaHumansInsurance, HealthMiddle AgedPregnancyPregnancy Complications, InfectiousPrevalenceRisk AssessmentYoung AdultZika Virus Infection

Identifiers

PMID32208419
PMCPMC7122809
OpenAlexW3012782494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.