Evidence map›Paper›PMID 32208350›Full record

ReviewCurrent opinion in cell biology2020

The multifunctional nature of mitochondrial contact site proteins.

Clare S Harper, Antoineen J White, Laura L Lackner

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mitochondrial Maintenance in Skeletal Muscle.Cold Spring Harbor perspectives in biology · 2025
    Review
  7. Mitochondria - the CEO of the cell.Journal of cell science · 2025
    Review
  8. Article
  9. Article
  10. Dysregulated inter-mitochondrial crosstalk in glioblastoma cells revealed by in situ cryo-electron tomography.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Clare S HarperDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Antoineen J WhiteDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Laura L LacknerDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA. Electronic address: Laura.Lackner@northwestern.edu.
Northwestern University · US

Funding

Developing Capacity to Evaluate Training Programs via Development of Human, Institutional and Social CapitalT32GM008449 · NIGMS · NORTHWESTERN UNIVERSITY · PI LEONARD, JOSHUA NATHANIEL · 1993 to 2023
$7.8M
Molecular Biophysics Training Program at Northwestern UniversityT32GM008382 · NIGMS · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 1990 to 2020
$4.3M
Investigating the molecular mechanism of mitochondrial tetheringR01GM120303 · NIGMS · NORTHWESTERN UNIVERSITY · PI LACKNER, LAURA L · 2017 to 2025
$2.9M
NIGMS NIH HHS R01 GM120303NIGMS NIH HHS T32 GM008382NIGMS NIH HHS T32 GM008449
6 · The paper itself

Abstract

Mitochondria make physical contact with nearly every other membrane in the cell, and these contacts have a wide variety of functions that are carried out by proteins that reside at the sites of contact. Over the past decade, tremendous insight into the identity and functions of proteins localized to mitochondrial contact sites has been gained. In doing so, it has become clear that one protein or protein complex can contribute to contact site formation and function in a wide variety of ways. Thus, complex and often surprising relationships between the roles of a mitochondrial contact site and its multifunctional resident proteins continue to be unraveled.

Indexed as

Endoplasmic ReticulumMitochondriaMitochondrial MembranesMitochondrial ProteinsModels, BiologicalMitochondrial ProteinsMembrane contact sitesMitochondriaMitochondrial contact sites

Identifiers

PMID32208350
PMCPMC7771046
OpenAlexW3012823307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.