Evidence map›Paper›PMID 32207996›Full record

Observational studyCirculation. Heart failure2020

Testing for Coronary Artery Disease in Older Patients With New-Onset Heart Failure: Findings From Get With The Guidelines-Heart Failure.

Kyle D O'Connor, Todd Brophy, Gregg C Fonarow, Ron Blankstein, Rajesh V Swaminathan, Haolin Xu, Roland A Matsouaka, Nancy M Albert, Eric J Velazquez, Clyde W Yancy and 3 more

Abstract readObservational Study
In one paragraph

Observational study in Circulation. Heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
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  4. Observational
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  15. Article
  16. Impact and Implications of Neurocognitive Dysfunction in the Management of Ischemic Heart Failure.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Kyle D O'ConnorDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC (K.D.O., R.V.S., H.X., R.A.M., A.F.H., A.D.D.).
Todd BrophyDepartment of Cardiovascular Medicine (T.B.).
Gregg C FonarowHeart and Vascular Institute, Cleveland Clinic, OH. Division of Cardiology, University of California, Los Angeles (G.C.F.).
Ron BlanksteinDivision of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA (R.B.).
Rajesh V SwaminathanDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC (K.D.O., R.V.S., H.X., R.A.M., A.F.H., A.D.D.).
Haolin XuDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC (K.D.O., R.V.S., H.X., R.A.M., A.F.H., A.D.D.).
Roland A MatsouakaDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC (K.D.O., R.V.S., H.X., R.A.M., A.F.H., A.D.D.).
Nancy M AlbertNursing Institute, Office of Nursing Research and Heart and Vascular Institute, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, OH (N.M.A.).
Eric J VelazquezDivision of Cardiology, Department of Medicine, Yale University School of Medicine, New Haven, CT (E.J.V.).
Clyde W YancyDivision of Cardiology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, IL (C.W.Y.).
Paul A HeidenreichVeterans Affairs Palo Alto Health Care System, Palo Alto, CA (P.A.H.).
Adrian F HernandezDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC (K.D.O., R.V.S., H.X., R.A.M., A.F.H., A.D.D.).
Adam D DeVoreDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC (K.D.O., R.V.S., H.X., R.A.M., A.F.H., A.D.D.).

Funding

NHLBI NIH HHS L30 HL124574
6 · The paper itself

Abstract

backgroundCurrent guidelines recommend evaluation for underlying heart disease and reversible conditions for patients with new-onset heart failure (HF). There are limited data on contemporary testing for coronary artery disease (CAD) in patients with new-onset HF.

methodsWe performed an observational cohort study using the Get With The Guidelines-Heart Failure registry linked to Medicare claims. All patients were aged ≥65 and hospitalized for new-onset HF from 2009 to 2015. We collected left ventricular ejection fraction (LVEF), prior HF history, and in-hospital CAD testing from the registry, as well as testing for CAD using claims from 90 days before to 90 days after index HF hospitalization.

resultsAmong 17 185 patients with new-onset HF, 6672 (39%) received testing for CAD, including 3997 (23%) during the index hospitalization. Testing for CAD differed by LVEF: 53% in HF with reduced EF (LVEF ≤40%), 42% in HF with borderline EF (LVEF, 41%-49%), and 31% in HF with preserved EF (LVEF ≥50%). After multivariable adjustment, patients who received testing for CAD, compared with those who did not, were younger and more likely to be male, have a smoking history, have hyperlipidemia, and have HF with reduced ejection fraction or HF with borderline ejection fraction (all

conclusionsThe majority of patients hospitalized for new-onset HF did not receive testing for CAD either during the hospitalization or in the 90 days before and after. The rates of testing for CAD were higher in patients with LVEF ≤40% though remained low. These data highlight an opportunity to improve care by identifying appropriate candidates for optimal CAD medical therapy and revascularization.

Indexed as

AgedAged, 80 and overAge FactorsCoronary Artery DiseaseDiagnostic Techniques, CardiovascularFemaleGuideline AdherenceHeart FailureHospitalizationHumansMaleMedicarePractice Guidelines as TopicPractice Patterns, Physicians'Predictive Value of TestsRegistriesatrial fibrillationcoronary artery diseaseheart failurehyperlipidemialeft ventricular dysfunction

Identifiers

PMID32207996
PMCPMC10790075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.