Evidence map›Paper›PMID 32207972›Full record

ArticleBiochemistry2020

Fluorescent Probes for Monitoring Serine Ubiquitination.

Kedar Puvar, Aya M Saleh, Ryan W Curtis, Yiyang Zhou, Prasanth R Nyalapatla, Jiaqi Fu, Alexander R Rovira, Yitzhak Tor, Zhao-Qing Luo, Arun K Ghosh and 4 more

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Covalent Probes To CaptureJournal of the American Chemical Society · 2024
    Article
  3. CapturingFrontiers in molecular biosciences · 2024
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kedar PuvarDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.
Aya M SalehWeldon School of Biomedical Engineering, Purdue University, 206 South Martin Jischke Drive, West Lafayette, Indiana 47906, United States.
Ryan W CurtisDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.
Yiyang ZhouDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.
Prasanth R NyalapatlaDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.
Jiaqi FuPurdue Institute of Immunology, Inflammation, and Infectious Diseases and Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47906, United States.
Alexander R RoviraDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0358, United States.
Yitzhak TorDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093-0358, United States.ORCID 0000-0003-3726-7799
Zhao-Qing LuoPurdue Institute of Immunology, Inflammation, and Infectious Diseases and Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47906, United States.
Arun K GhoshDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.ORCID 0000-0003-2472-1841
Mary J WirthDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.ORCID 0000-0003-2538-6985
Jean ChmielewskiDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.ORCID 0000-0003-4958-7175
Tamara L Kinzer-UrsemWeldon School of Biomedical Engineering, Purdue University, 206 South Martin Jischke Drive, West Lafayette, Indiana 47906, United States.
Chittaranjan DasDepartment of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47906, United States.ORCID 0000-0002-0567-7753

Funding

Fluorescent Nucleosides and OligonucleotidesR01GM069773 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TOR, YITZHAK · 2004 to 2020
$5.0M
Mechanism of atypical ubiquitination and deubiquitination by bacterial effectorsR01GM126296 · NIGMS · PURDUE UNIVERSITY · PI Chittaranjan Das · 2018 to 2026
$3.6M
Design & Synthesis of Nonpeptide Protease InhibitorsR37AI150466 · NIAID · PURDUE UNIVERSITY · PI GHOSH, ARUN K · 2019 to 2020
$969k
NIAID NIH HHS R37 AI150466NIGMS NIH HHS R01 GM069773NIGMS NIH HHS R01 GM126296
6 · The paper itself

Abstract

In a radical departure from the classical E1-E2-E3 three-enzyme mediated ubiquitination of eukaryotes, the recently described bacterial enzymes of the SidE family of

Indexed as

Adenosine DiphosphateAmino Acid MotifsBacterial ProteinsBiochemistryFluorescent DyesLegionella pneumophilaNADSerineUbiquitinationAdenosine DiphosphateBacterial ProteinsFluorescent DyesNADSerine

Identifiers

PMID32207972
PMCPMC7294441

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.