Evidence map›Paper›PMID 32207883›Full record

ArticleMicrobial biotechnology2020

The potential use of the Penicillium chrysogenum antifungal protein PAF, the designed variant PAF

Liliána Tóth, Éva Boros, Péter Poór, Attila Ördög, Zoltán Kele, Györgyi Váradi, Jeanett Holzknecht, Doris Bratschun-Khan, István Nagy, Gábor K Tóth and 3 more

Open access · goldAbstract read
In one paragraph

Article in Microbial biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  5. Review
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  7. Review
  8. Article
  9. Article
  10. TheMicroorganisms · 2023
    Article
  11. TheJournal of fungi (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. The combination ofBioControl (Dordrecht, Netherlands) · 2022
    Article
  16. Potential of Antifungal Proteins (AFPs) to ControlJournal of fungi (Basel, Switzerland) · 2021
    Article
  17. Article
  18. Article
  19. Biofungicidal Potential ofFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Liliána TóthInstitute of Plant Biology, Biological Research Centre, Temesvári krt. 62, H-6726, Szeged, Hungary.
Éva BorosInstitute of Biochemistry, Biological Research Centre, Temesvári krt. 62, H-6726, Szeged, Hungary.
Péter PoórDepartment of Plant Biology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H-6726, Szeged, Hungary.
Attila ÖrdögDepartment of Plant Biology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H-6726, Szeged, Hungary.
Zoltán KeleDepartment of Medical Chemistry, Faculty of Medicine, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.
Györgyi VáradiDepartment of Medical Chemistry, Faculty of Medicine, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.
Jeanett HolzknechtInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria.
Doris Bratschun-KhanInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria.
István NagyInstitute of Biochemistry, Biological Research Centre, Temesvári krt. 62, H-6726, Szeged, Hungary.
Gábor K TóthDepartment of Medical Chemistry, Faculty of Medicine, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary.
Gábor RákhelyDepartment of Biotechnology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H-6726, Szeged, Hungary.
Florentine MarxInstitute of Molecular Biology, Biocenter, Medical University of Innsbruck, Innrain 80-82, A-6020, Innsbruck, Austria.
László GalgóczyInstitute of Plant Biology, Biological Research Centre, Temesvári krt. 62, H-6726, Szeged, Hungary.ORCID 0000-0002-6976-8910
University of Szeged · HUHUN-REN Szegedi Biológiai Kutatóközpont · HUInnsbruck Medical University · AT

Funding

Austrian Science Fund FWF I 3132
6 · The paper itself

Abstract

The prevention of enormous crop losses caused by pesticide-resistant fungi is a serious challenge in agriculture. Application of alternative fungicides, such as antifungal proteins and peptides, provides a promising basis to overcome this problem; however, their direct use in fields suffers limitations, such as high cost of production, low stability, narrow antifungal spectrum and toxicity on plant or mammalian cells. Recently, we demonstrated that a Penicillium chrysogenum-based expression system provides a feasible tool for economic production of P. chrysogenum antifungal protein (PAF) and a rational designed variant (PAF

Indexed as

PenicilliumPenicillium chrysogenumAnimalsAntifungal AgentsBotrytisFungal ProteinsPeptidesAntifungal AgentsFungal ProteinsPeptides

Identifiers

PMID32207883
PMCPMC7415367
OpenAlexW3012722666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.