Evidence map›Paper›PMID 32207771›Full record

ArticleAmerican journal of epidemiology2020

The Epidemiologic Toolbox: Identifying, Honing, and Using the Right Tools for the Job.

Catherine R Lesko, Alexander P Keil, Jessie K Edwards

Abstract read
In one paragraph

Article in American journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Unmet needs among long-term breast cancer survivors.Cancer causes & control : CCC · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. On the Need to Revitalize Descriptive Epidemiology.American journal of epidemiology · 2022
    Article
  8. Observational
  9. The Global Emergence of Human Babesiosis.Pathogens (Basel, Switzerland) · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Catherine R Lesko
Alexander P Keil
Jessie K Edwards

Funding

Public health priority setting for environmental metals mixtures and birth defectsR01ES029531 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FRY, REBECCA · 2018 to 2021
$1.2M
Unhealthy alcohol use, other drug use, and mental health disorders: comorbidity burden in people with HIV, gaps in treatment, and impact on the HIV care continuumK01AA028193 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI LESKO, CATHERINE · 2019 to 2023
$900k
Comparative effectiveness of tailored HIV treatment plans and mortalityK01AI125087 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI EDWARDS, JESSIE · 2017 to 2021
$586k
NIAAA NIH HHS K01 AA028193NIAID NIH HHS K01 AI125087NIEHS NIH HHS R01 ES029531
6 · The paper itself

Abstract

There has been much debate about the relative emphasis of the field of epidemiology on causal inference. We believe this debate does short shrift to the breadth of the field. Epidemiologists answer myriad questions that are not causal and hypothesize about and investigate causal relationships without estimating causal effects. Descriptive studies face significant and often overlooked inferential and interpretational challenges; we briefly articulate some of them and argue that a more detailed treatment of biases that affect single-sample estimation problems would benefit all types of epidemiologic studies. Lumping all questions about causality creates ambiguity about the utility of different conceptual models and causal frameworks; 2 distinct types of causal questions include 1) hypothesis generation and theorization about causal structures and 2) hypothesis-driven causal effect estimation. The potential outcomes framework and causal graph theory help efficiently and reliably guide epidemiologic studies designed to estimate a causal effect to best leverage prior data, avoid cognitive fallacies, minimize biases, and understand heterogeneity in treatment effects. Appropriate matching of theoretical frameworks to research questions can increase the rigor of epidemiologic research and increase the utility of such research to improve public health.

Indexed as

CausalityEpidemiologic MethodsBiasHumansModels, TheoreticalPublic Healthbiascausalitydescriptive studiesepidemiologic methodsinference

Identifiers

PMID32207771
PMCPMC7368131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.