ArticleBJS open2020
Factors affecting mortality after traumatic brain injury in a resource-poor setting.
Article in BJS open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of early adjunctive pharmacotherapy on serum levels of brain injury biomarkers in patients with traumatic brain injury: a systematic review of randomized controlled studies.Frontiers in pharmacology · 2023Pooled it
- Preventable trauma deaths and health system strengthening recommendations: findings from a multi-disciplinary expert panel review of trauma deaths in the Western Cape, South Africa.BMC public health · 2025Article
- Navigating Limitations and Clinical Challenges in Indonesian Tertiary Trauma Center for Penetrating Brain Injury: A Case Report and Literature Review.Asian journal of neurosurgery · 2025Article
- Predicting Factors Associated with In-hospital Mortality in Traumatic Brain Injury.Asian journal of neurosurgery · 2025Article
- Mortality Predictors for Adult Patients with Mild-to-Moderate Traumatic Brain Injury: A Literature Review.Neurology international · 2024Review
- Outcomes of traumatic brain injury patients with acute epidural and subdural hematoma who underwent burr hole surgery: A two-year study at Kilimanjaro Christian Medical Centre, Tanzania.World neurosurgery: X · 2024Article
- Platelet-to-lymphocyte ratio as a prognostic predictive marker on adults with traumatic brain injury: Systematic review.Surgical neurology international · 2024Review
- Article
- Machine Learning Algorithm Predicts Mortality Risk in Intensive Care Unit for Patients with Traumatic Brain Injury.Diagnostics (Basel, Switzerland) · 2023Article
- Epidemiology of Traumatic Brain Injury in Iran: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2023Review
- Expert consensus on blood pressure management in critically ill patients.Journal of intensive medicine · 2023Article
- Traumatic brain injury and immunological outcomes: the double-edged killer.Future science OA · 2023Review
- Incidence and predictors of mortality among traumatic brain injury patients admitted to Amhara region Comprehensive Specialized Hospitals, northwest Ethiopia, 2022.BMC emergency medicine · 2023Article
- Epidemiological features of traumatic brain injuries from a first-level trauma care national medical center in Georgia.One health & risk management · 2023Article
- Traumatic Brain Injury Cases' Mortality Predictors, Association, and Outcomes in the Emergency Department at a Tertiary Healthcare Center in Saudi Arabia.Asian journal of neurosurgery · 2022Article
- Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients.Pediatric surgery international · 2022Article
- Transorbital penetrating cerebellar injury in a 10-year-old girl.Radiology case reports · 2022Article
- Brain-lung interaction: a vicious cycle in traumatic brain injury.Acute and critical care · 2022Article
- Traumatic brain injury: Association between the Glasgow Coma Scale score and intensive care unit mortality.The Southern African journal of critical care : the official journal of the Critical Care Society · 2022Article
- Epidemiology of Traumatic Brain Injury in Georgia: A Prospective Hospital-Based Study.Risk management and healthcare policy · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraumatic brain injury (TBI) is a major cause of long-term disability and economic loss to society. The aim of this study was to assess the factors affecting mortality after TBI in a resource-poor setting.
methodsChart review was performed for randomly selected patients who presented with TBI between 2013 and 2017 at St Mary's Hospital, Lacor, northern Uganda. Data collected included demographic details, time from injury to presentation, and vital signs on arrival. In-hospital management and mortality were recorded. Severe head injury was defined as a Glasgow Coma Scale score below 9.
resultsA total of 194 patient charts were reviewed. Median age at time of injury was 27 (i.q.r. 2-68) years. The majority of patients were male (M : F ratio 4·9 : 1). Some 30·9 per cent of patients had severe head injury, and an associated skull fracture was observed in 8·8 per cent. Treatment was mainly conservative in 94·8 per cent of patients; three patients (1·5 per cent) had burr-holes, four (2·1 per cent) had a craniotomy, and three (1·5 per cent) had skull fracture elevation. The mortality rate was 33·0 per cent; 46 (72 per cent) of the 64 patients who died had severe head injury. Of the ten surgically treated patients, seven died, including all three patients who had a burr-hole. In multivariable analysis, factors associated with mortality were mean arterial pressure (P = 0·012), referral status (P = 0·001), respiratory distress (P = 0·040), severe head injury (P = 0·011) and pupil reactivity (P = 0·011).
conclusionTBI in a resource-poor setting remains a major challenge and affects mainly young males. Decisions concerning surgical intervention are compromised by the lack of both CT and intracranial pressure monitoring, with consequent poor outcomes.
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