Evidence map›Paper›PMID 32207528›Full record

ArticleMilitary medicine2020

HIV Care Continuum and Meeting 90-90-90 Targets: Cascade of Care Analyses of a U.S. Military Cohort.

Andrew Anglemyer, Noah Haber, Adi Noiman, George Rutherford, Anuradha Ganesan, Jason Blaylock, Jason Okulicz, Ryan C Maves, Tahaniyat Lalani, Christina Schofield and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Military medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 2 countries.

Andrew AnglemyerDepartment of Operations Research, Naval Postgraduate School, 1 University Circle, Monterey, CA 93943, USA.
Noah HaberCarolina Population Center, University of North Carolina, 123 W Franklin St, Chapel Hill, NC 27516, USA.
Adi NoimanInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20852, USA.
George RutherfordPrevention and Public Health Group, Epidemiology and Biostatistics, University of California San Francisco, 550 16th Street, Second Floor, San Francisco, CA 94158, USA.
Anuradha GanesanInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20852, USA.
Jason BlaylockDivision of Infectious Diseases, Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20889, USA.
Jason OkuliczInfectious Disease Service, Brooke Army Medical Center, 3551 Roger Brooke Dr. Fort Sam Houston, TX 78234, USA.
Ryan C MavesDivision of Infectious Diseases, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego CA, 92134, TX 78234, USA.
Tahaniyat LalaniInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20852, USA.
Christina SchofieldDivision of Infectious Diseases, Madigan Army Medical Center, 9040A, Jackson Ave, Joint Base Lewis-McChord, WA 98431, TX 78234, USA.
James MancusoArmed Forces Health Surveillance Branch, 7700 Arlington Boulevard, Suite 5101, Falls Church, VA 22042, USA.
Brian K AganInfectious Disease Clinical Research Program, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20852, USA.
Infectious Disease Clinical Research Program HIV Working Group
Walter Reed National Military Medical Center · USArmed Forces Health Surveillance Center · USHenry M. Jackson Foundation · USMadigan Army Medical Center · USNaval Medical Center Portsmouth · USNaval Medical Center San Diego · USNaval Postgraduate School · USSan Antonio Military Medical Center · USStanford University · USUniformed Services University of the Health Sciences · USUniversity of California, San Francisco · US

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
NICHD NIH HHS P2C HD050924
6 · The paper itself

Abstract

introductionThe new initiative by the Department of Health and Human Services (DHHS) aims to decrease new HIV infections in the U.S. by 75% within 5 years and 90% within 10 years. Our objective was to evaluate whether the U.S. military provides a good example of the benefits of such policies. MATERIALS AND

methodsWe conducted an analysis of a cohort of 1,405 active duty military personnel with HIV enrolled in the Natural History Study who were diagnosed between 2003 and 2015 at six U.S. military medical centers. The study was approved by institutional review boards at the Uniformed Services University of the Health Sciences and each of the sites. We evaluated the impact of Department of Defense (DoD) HIV care policies, including screening, linkage to care, treatment eligibility, and combined antiretroviral therapy (cART) initiation on achieving viral suppression (VS) within 3 years of diagnosis. As a secondary outcome, we evaluated the DoD's achievement of UNAIDS 90-90-90 targets.

resultsNearly all (99%) were linked to care within 60 days. Among patients diagnosed in 2003-2009, 77.5% (95% confidence intervals (CI) 73.9-80.6%) became eligible for cART within 3 years of diagnosis, 70.6% (95% CI 66.6-74.1%) overall initiated cART, and 64.2% (95% CI 60.1-68.0%) overall achieved VS. Among patients diagnosed in 2010-2015, 98.7% (95% CI 96.7-99.5%) became eligible for cART within 3 years of diagnosis, 98.5% (95% CI 96.4-99.4%) overall initiated cART, and 89.8% (95% CI 86.0-92.5%) overall achieved VS.

conclusionsU.S. military HIV policies have been highly successful in achieving VS goals, exceeding the UNAIDS 90-90-90 targets. In spite of limitations, including generalizability, this example demonstrates the feasibility of the DHHS initiative to decrease new infections through testing, early treatment, and retention in care.

Indexed as

Continuity of Patient CareMilitary PersonnelAdultAntiretroviral Therapy, Highly ActiveCohort StudiesFemaleHIV InfectionsHospitals, MilitaryHumansMaleMass ScreeningViral Load

Identifiers

PMID32207528
PMCPMC7429920
OpenAlexW3012600719

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.