Evidence map›Paper›PMID 32207106›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2020

Extrusion-Based Bioprinting: Current Standards and Relevancy for Human-Sized Tissue Fabrication.

Kelsey Willson, Dongxu Ke, Carlos Kengla, Anthony Atala, Sean V Murphy

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.Biomedical materials & devices (New York, N.Y.) · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Next Stage Approach to Tissue Engineering Skeletal Muscle.Bioengineering (Basel, Switzerland) · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kelsey WillsonWake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA.
Dongxu KeWake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA.
Carlos KenglaWake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA.
Anthony AtalaWake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA.
Sean V MurphyWake Forest Institute for Regenerative Medicine, Wake Forest University, Winston-Salem, NC, USA. semurphy@wakehealth.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The field of bioengineering has long pursued the goal of fabricating large-scale tissue constructs for use both in vitro and in vivo. Recent technological advances have indicated that bioprinting will be a key technique in manufacturing these specimens. This chapter aims to provide an overview of what has been achieved to date through the use of microextrusion bioprinters and what major challenges still impede progress. Microextrusion printer configurations will be addressed along with critical design characteristics including nozzle specifications and bioink modifications. Significant challenges within the field with regard to achieving long-term cell viability and vascularization, and current research that shows promise in mitigating these challenges in the near future are discussed. While microextrusion is a broad field with many applications, this chapter aims to provide an overview of the field with a focus on its applications toward human-sized tissue constructs.

Indexed as

Biocompatible MaterialsPrinting, Three-DimensionalArtificial OrgansBioprintingCell SurvivalEquipment DesignHumansMaterials TestingMicrovesselsOrgan SizeRheologyShear StrengthTissue EngineeringTissue ScaffoldsBiocompatible Materials3D printingBioinkBioprintingCell printingMicroextrusion printingNozzleRheologyVascularization

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.