ReviewFolia microbiologica2020
Review: antimicrobial properties of allicin used alone or in combination with other medications.
Review in Folia microbiologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 87 citations in OpenAlex.
- Attenuation of DOX-Associated Biochemical and Histological Brain Alterations.Veterinary medicine and science · 2026Article
- Inhalable Spray-Dried Carriers for Deep Lung Delivery and In Situ Synthesis of Allicin.ACS omega · 2026Article
- Role of Plant-Derived Antioxidants in Oxidative Stress-Associated Myocardial Infarction: Structure-Activity Relationship (SAR)-Based Mechanistic Insights.Molecules (Basel, Switzerland) · 2026Review
- Allium-Derived Compounds Against Multidrug-Resistant Bacteria: Antibacterial Activity and Synergistic Effects.ChemMedChem · 2026Article
- Therapeutic potential of garlic-derived exosome like nanovesicles: challenge and opportunity.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026Review
- Shelf-Life Extension of Chicken Fillets Using Flaxseed Mucilage Coatings Incorporated With Bixin-Allicin or Bixin-Orange Peel Essential Oil Nanoemulsions.Food science & nutrition · 2026Article
- Organosulfur compounds as dual-action agents: a critical review of antimicrobial and immunomodulatory potentials, and translational barriers.Frontiers in pharmacology · 2026Review
- Application of quercetin enhances tobacco resistance to Phytophthora nicotianae.Functional & integrative genomics · 2025Article
- Advancement in nanocarrier-mediated delivery of herbal bioactives: from bench to beside.Natural products and bioprospecting · 2025Review
- Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects.Discover oncology · 2025Review
- Footprint of Domestic Processing on Safety and Functional Properties of Italian Black Garlic.Foods (Basel, Switzerland) · 2025Article
- Computational study of the therapeutic properties of allicin and its nanocomplexes using DFT and molecular docking techniques.Scientific reports · 2025Article
- A Review on Novel Techniques Used for Drying Medicinal Plants and Its Applications.International journal of biomaterials · 2025Review
- Natural Antimicrobial Compounds as Promising Preservatives: A Look at an Old Problem from New Perspectives.Molecules (Basel, Switzerland) · 2024Review
- Capsaicin: Emerging Pharmacological and Therapeutic Insights.Current issues in molecular biology · 2024Review
- Article
- NMR Metabolite Profiling for the Characterization of Vessalico Garlic Ecotype and Bioactivity againstPlants (Basel, Switzerland) · 2024Article
- In Vitro Activity ofVeterinary sciences · 2024Article
- You must be myths-taken: Examining belief in falsehoods during the COVID-19 health crisis.PloS one · 2024Article
- Garlic-Derived Quorum Sensing Inhibitors: A Novel Strategy Against Fungal Resistance.Drug design, development and therapy · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Garlic (Allium sativum L.) is a well-known spice widely utilised for its medicinal properties. There is an extensive record of the many beneficial health effects of garlic which can be traced back to as early as the ancient Egyptian era. One of the most studied properties of garlic is its ability to cure certain ailments caused by infections. In the 1940s, the antimicrobial activities exhibited by garlic were first reported to be due to allicin, a volatile compound extracted from raw garlic. Since then, allicin has been widely investigated for its putative inhibitory activities against a wide range of microorganisms. Allicin has demonstrated a preference for targeting the thiol-containing proteins and/or enzymes in microorganisms. It has also demonstrated the ability to regulate several genes essential for the virulence of microorganisms. Recently, it was reported that allicin may function better in combination with other antimicrobials compared to when used alone. When used in combination with antibiotics or antifungals, allicin enhanced the antimicrobial activities of these substances and improved the antimicrobial efficacy. Hence, it is likely that combination therapy of allicin with additional antimicrobial drug(s) could serve as a viable alternative for combating rising antimicrobial resistance. This review focuses on the antimicrobial activities exhibited by allicin alone as well as in combination with other substances. The mechanisms of action of allicin elucidated by some of the studies are also highlighted in the present review in order to provide a comprehensive overview of this versatile bioactive compound and the mechanistic evidence supporting its potential use in antimicrobial therapy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.