Evidence map›Paper›PMID 32207049›Full record

ArticleObesity surgery2020

The Causes of Gastroesophageal Reflux after Laparoscopic Sleeve Gastrectomy: Quantitative Assessment of the Structure and Function of the Esophagogastric Junction by Magnetic Resonance Imaging and High-Resolution Manometry.

Giuseppe Quero, Claudio Fiorillo, Bernard Dallemagne, Pietro Mascagni, Jelena Curcic, Mark Fox, Silvana Perretta

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01980420 (Prospective Study of the Impact of Sleeve Gastrectomy on Gastro-esophageal Junction Function), which is not on this map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01980420 nacompletednot on this map

Prospective Study of the Impact of Sleeve Gastrectomy on Gastro-esophageal Junction Function

TypeinterventionalSponsorIHU StrasbourgRan2013 to 2016Enrolled35ConditionsMorbid ObesityArmsLaparoscopic sleeve gastrectomy
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

Giuseppe QueroIHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.
Claudio FiorilloIHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France. claudio.fiorillo@hotmail.it.ORCID http://orcid.org/0000-0001-7681-3567
Bernard DallemagneIRCAD, Research Institute against Digestive Cancer, Strasbourg, France.
Pietro MascagniIHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.
Jelena CurcicDepartment of Gastroenterology and Hepatology, University Hospital Zürich, CH-8091, Zürich, Switzerland.
Mark FoxDepartment of Gastroenterology and Hepatology, University Hospital Zürich, CH-8091, Zürich, Switzerland.
Silvana PerrettaIHU-Strasbourg, Institute of Image-Guided Surgery, Strasbourg, France.
Agostino Gemelli University Polyclinic · ITInstitut de Recherche contre les Cancers de l’Appareil Digestif · FRUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of de novo gastroesophageal reflux disease (GERD) after LSG is substantial. However, an objective correlation with the structural gastric and EGJ changes has not been demonstrated yet. We aimed to prospectively evaluate the effects of laparoscopic sleeve gastrectomy (LSG) on the structure and function of the esophagogastric junction (EGJ) and stomach.

methodsInvestigations were performed before and after > 50% reduction in excess body weight (6-12 months after LSG). Subjects with GERD at baseline were excluded. Magnetic Resonance Imaging (MRI), high-resolution manometry (HRM), and ambulatory pH-impedance measurements were used to assess the structure and function of the EGJ and stomach before and after LSG.

resultsFrom 35 patients screened, 23 (66%) completed the study (age 36 ± 10 years, BMI 42 ± 5 kg/m

conclusionLSG has multiple effects on the EGJ and stomach that facilitate reflux. In particular, EGJ disruption as indicated by increased (more obtuse) esophagogastric insertion angle and small gastric capacity were associated with the risk of GERD after LSG. clinicaltrials.gov: NCT01980420.

Indexed as

Gastroesophageal RefluxLaparoscopyObesity, MorbidAdultEsophagogastric JunctionGastrectomyHumansMagnetic Resonance ImagingManometryMiddle AgedGERDLaparoscopic Sleeve GastrectomyMagnetic Resonance Imaging (MRI)

Identifiers

PMID32207049
OpenAlexW3012681378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.