Evidence map›Paper›PMID 32206947›Full record

ArticleMolecular and cellular biochemistry2020

High-protein diet and omega-3 fatty acids improve redox status in olanzapine-treated rats.

Miroslav Mitrovic, Tamara Nikolic Turnic, Vladimir Zivkovic, Zarko Pavic, Aleksandra Vranic, Ivan Srejovic, Jasmina Sretenovic, Sergey Bolevich, Vladimir Lj Jakovljevic

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In one paragraph

Article in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miroslav MitrovicPharmanova Pharmaceutical Company, 8 Industrijska, 11000, Belgrade, Serbia.
Tamara Nikolic TurnicDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica St, 34000, Kragujevac, Serbia.
Vladimir ZivkovicDepartment of Physiology, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica St., 34000, Kragujevac, Serbia.
Zarko PavicHigh School of Applied Medical Studies "Medica", 8 Mitropolita Petra St., 11000, Belgrade, Serbia.
Aleksandra VranicDepartment of Pharmacy, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica St, 34000, Kragujevac, Serbia.
Ivan SrejovicDepartment of Physiology, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica St., 34000, Kragujevac, Serbia.
Jasmina SretenovicDepartment of Physiology, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica St., 34000, Kragujevac, Serbia.
Sergey BolevichDepartment of Human Pathology, 1st Moscow State Medical University IM Sechenov, Trubetskaya str. 2, Moscow, Russian Federation, 119992.
Vladimir Lj JakovljevicDepartment of Physiology, Faculty of Medical Sciences, University of Kragujevac, 69 Svetozara Markovica St., 34000, Kragujevac, Serbia. drvladakgbg@yahoo.com.

Funding

Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia JP 01/15Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia JP 03/18
6 · The paper itself

Abstract

The present study aimed to estimate the effects of high-protein diet (PD)-isolated whey protein and omega-3 fatty acids-docosahexaenoic and eicosapentaenoic acid on oxidative parameters of rats treated with Olanzapine (OLZ). Experiments were carried out on 8-week-old Wistar albino male rats (n = 64) weighing 200 ± 20 g. By dietary and pharmacological treatment, all animals were divided into 8 groups: 1. CTRL group; 2. CTRL + OLZ group; 3. CTRL + FA group; 4. CTRL + OLZ + FA group; 5. PD group; 6. PD + OLZ group; 7. PD + FA group; 8. PD + OLZ + FA group. After 6 weeks of pharmacological/diet treatment, all animals were sacrificed to collect blood samples and determine the biomarkers of oxidative stress. The following oxidative stress markers were measured spectrophotometrically: superoxide anion radical (O

Indexed as

Diet, High-ProteinAnimalsAntioxidantsAntipsychotic AgentsCatalaseFatty Acids, Omega-3GlutathioneHydrogen PeroxideLipid PeroxidationMaleNitric OxideOlanzapineOxidation-ReductionOxidative StressRatsRats, WistarAntioxidantsAntipsychotic AgentsCatalaseFatty Acids, Omega-3GlutathioneHydrogen PeroxideNitric OxideOlanzapineSuperoxide DismutaseThiobarbituric Acid Reactive SubstancesHigh-protein dietOlanzapineOmega-3 fatty acidsOxidative stressRats

Identifiers

PMID32206947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.