Evidence map›Paper›PMID 32206927›Full record

ArticleClinical and experimental medicine2020

Altered ratio of circulating follicular regulatory T cells and follicular helper T cells during primary EBV infection.

Jiang Qian, Qinhua Yu, Guoqing Chen, Mingxia Wang, Zhao Zhao, Yueyue Zhang, Liannv Qiu

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jiang QianCollege of Medical Technology, Zhejiang Chinese Medical University, Hangzhou, China.
Qinhua YuDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou, 310014, China.
Guoqing ChenDepartment of Pediatrics, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, China.
Mingxia WangSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
Zhao ZhaoDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou, 310014, China.
Yueyue ZhangSchool of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
Liannv QiuDepartment of Clinical Laboratory, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 158 Shangtang Road, Hangzhou, 310014, China. qlv2012@126.com.ORCID http://orcid.org/0000-0003-3944-4509
Zhejiang Provincial People's Hospital · CNWenzhou Medical University · CNZhejiang Chinese Medical University · CN

Funding

Natural Science Foundation of Zhejiang Province Y18H200014
6 · The paper itself

Abstract

Follicular help T cells (Tfh) play an important role in the activation and differentiation of B cells, while follicular regulatory T cells (Tfr) control Tfh and resulting humoral immune responses. Accumulating evidence has demonstrated that the dysregulation of Tfr contributed to the pathogenesis of infectious diseases. However, the role of Tfr in Epstein-Barr virus (EBV) infection remains lacking. Fifty-five EBV-infected infectious mononucleosis (IM) patients and 21 healthy individuals (HIs) were recruited in the study. We investigated the number of Tfr (FoxP3

Indexed as

Case-Control StudiesCell DifferentiationChildChild, PreschoolEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHumansInfectious MononucleosisMaleT Follicular Helper CellsT-Lymphocytes, RegulatoryViral LoadEpstein–Barr virusFlow cytometryFollicular helper T cellsFollicular regulatory T cellsInfectious mononucleosis

Identifiers

PMID32206927
PMCPMC7366583
OpenAlexW3012632931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.