ArticleJournal of Alzheimer's disease reports2020
Identification of Superficial White Matter Abnormalities in Alzheimer's Disease and Mild Cognitive Impairment Using Diffusion Tensor Imaging.
Article in Journal of Alzheimer's disease reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- The application of diffusion tensor imaging in patients with mild cognitive impairment: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- A high-resolution functional network-organized atlas of human superficial white matter from ultra-high-field diffusion MRI.iScience · 2026Article
- Superficial white matter and gray matter jointly support cognition among older adults in India.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Microstructural changes in memory-related brain regions of stroke-free patients with middle cerebral artery occlusion as revealed by diffusion spectrum imaging.Brain imaging and behavior · 2026Review
- A DTI-Radiomics and Clinical Integration Model for Predicting MCI-to-AD Progression Using Corpus Callosum Features.Current Alzheimer research · 2026Article
- Assessing biological self-organization patterns using statistical complexity characteristics: a tool for diffusion tensor imaging analysis.Magma (New York, N.Y.) · 2025Article
- Association of Superficial White Matter Microstructure With Cortical Pathology Deposition Across Early Stages of the AD Continuum.Neurology · 2025Article
- U-fiber diffusion kurtosis and susceptibility characteristics in relapsing-remitting multiple sclerosis may be related to cognitive deficits and neurodegeneration.European radiology · 2024Article
- Imaging of the superficial white matter in health and disease.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Superficial white matter across development, young adulthood, and aging: volume, thickness, and relationship with cortical features.Brain structure & function · 2023Article
- Short superficial white matter and aging: a longitudinal multi-site study of 1293 subjects and 2711 sessions.Aging brain · 2023Article
- Superficial white matter microstructure affects processing speed in cerebral small vessel disease.Human brain mapping · 2022Article
- Brain pathological changes during neurodegenerative diseases and their identification methods: How does QSM perform in detecting this process?Insights into imaging · 2022Review
- Article
- Machine learning to investigate superficial white matter integrity in early multiple sclerosis.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
- Diffusion Tensor Imaging Profiles Can Distinguish Diffusivity and Neural Properties of White Matter Injury in Hydrocephalus vs. Non-hydrocephalus Using a Strategy of a Periodic Table of DTI Elements.Frontiers in neurology · 2022Article
- Differences in structural MRI and diffusion tensor imaging underlie visuomotor performance declines in older adults with an increased risk for Alzheimer's disease.Frontiers in aging neuroscience · 2022Article
- The Neural Mechanisms of Tinnitus: A Perspective From Functional Magnetic Resonance Imaging.Frontiers in neuroscience · 2021Review
- Loss and dispersion of superficial white matter in Alzheimer's disease: a diffusion MRI study.Brain communications · 2021Article
- Using Fractional Anisotropy Imaging to Detect Mild Cognitive Impairment and Alzheimer's Disease among Mexican Americans and Non-Hispanic Whites: A HABLE Study.Dementia and geriatric cognitive disorders · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDiffusion tensor imaging (DTI) estimates the microstructural alterations of the brain, as a magnetic resonance imaging (MRI)-based neuroimaging technique. Prior DTI studies reported decreased structural integrity of the superficial white matter (SWM) in the brain diseases.
objectiveThis study aimed to determine the diffusion characteristics of SWM in Alzheimer's disease (AD) and mild cognitive impairment (MCI) using tractography and region of interest (ROI) approaches.
methodsThe diffusion MRI data were downloaded from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database on 24 patients with AD, 24 with MCI, and 24 normal control (NC) subjects. DTI processing was performed using DSI Studio software. First, for ROI-based analysis, The superficial white matter was divided into right and left frontal, parietal, temporal, insula, limbic and occipital regions by the Talairach Atlas, Then, for tractography-based analysis, the tractography of each of these regions was performed with 100000 seeds. Finally, the average diffusion values were extracted from voxels within the ROIs and tracts.
resultsBoth tractography and ROI analyses showed a significant difference in radial, axial and mean diffusivity values between the three groups (
conclusionDTI provided information indicating microstructural changes in the SWM of patients with AD and MCI. Therefore, assessment of the SWM using DTI may be helpful for the clinical diagnosis of patients with AD and MCI.
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