Evidence map›Paper›PMID 32206724›Full record

ArticleScience advances2020

TRPC1 participates in the HSV-1 infection process by facilitating viral entry.

DongXu He, AiQin Mao, YouRan Li, SiuCheung Tam, YongTang Zheng, XiaoQiang Yao, Lutz Birnbaumer, Indu S Ambudkar, Xin Ma

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Transient receptor potential channels inChannels (Austin, Tex.) · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. RTP4 Enhances Corneal HSV-1 Infection in Mice With Type 2 Diabetes Mellitus.Investigative ophthalmology & visual science · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Mechanisms and significance of CaCurrent opinion in physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

DongXu HeWuxi School of Medicine and School of Food Science and Technology, Jiangnan University, Jiangsu, China.ORCID 0000-0003-3950-8584
AiQin MaoWuxi School of Medicine and School of Food Science and Technology, Jiangnan University, Jiangsu, China.
YouRan LiSchool of Biotechnology, Jiangnan University, Jiangsu, China.
SiuCheung TamSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
YongTang ZhengKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
XiaoQiang YaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-0687-8186
Lutz BirnbaumerLaboratory of Signal Transduction, NIEHS, NIH, Research Triangle Park, NC, USA.
Indu S AmbudkarSecretory Physiology Section, MPTB, NIDCR, NIH, Bethesda, MD, USA.ORCID 0000-0002-9559-8679
Xin MaWuxi School of Medicine and School of Food Science and Technology, Jiangnan University, Jiangsu, China.ORCID 0000-0001-8525-068X
Jiangnan University · CNChinese University of Hong Kong · HKKunming Institute of Zoology · CNOffice of the Director · USPontificia Universidad Católica Argentina · AR

Funding

Molecular Mechanisms Regulating Calcium Flux In Salivary GlandsZIADE000438 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI AMBUDKAR, INDU S. · 2009 to 2025
$42.5M
Molecular Regulaton Calcium Flux In Salivary GlandsZ01DE000438 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI AMBUDKAR, INDU S. · 1987 to 2008
$3.6M
Transmembrane Signaling Mechanisms Involving TRP ChannelsZ01ES101684 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BIRNBAUMER, LUTZ · 2003 to 2008
$2.1M
Intramural NIH HHS Z01 DE000438Intramural NIH HHS Z01 ES101684
6 · The paper itself

Abstract

Mammalian transient receptor potential (TRP) channels are major components of Ca

Indexed as

Host-Pathogen InteractionsVirus InternalizationAnimalsCalciumCell Line, TumorChlorocebus aethiopsHerpes SimplexHerpesvirus 1, HumanHumansIon Channel GatingMiceModels, BiologicalMutationProtein BindingTRPC Cation ChannelsVero CellsCalciumtransient receptor potential cation channel, subfamily C, member 1TRPC Cation Channels

Identifiers

PMID32206724
PMCPMC7080438
OpenAlexW3012524124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.