Evidence map›Paper›PMID 32206695›Full record

ArticleVirusdisease2020

In vitro anti-HIV-1 activity of ethyl gallate.

C Muddu Krishna, J N Kolla, S Asha, T Sravan Kumar Reddy

Open access · bronzeAbstract read
In one paragraph

Article in Virusdisease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

C Muddu KrishnaDepartment of Biotechnology, VFSTR (Deemed to be University), Vadlamudi, Guntur, A.P. India.
J N Kolla2Discovery Biology, Hetero Research Foundation, Hyderabad, Telangana India.
S AshaDepartment of Biotechnology, VFSTR (Deemed to be University), Vadlamudi, Guntur, A.P. India.
T Sravan Kumar Reddy2Discovery Biology, Hetero Research Foundation, Hyderabad, Telangana India.
Hetero Drugs (India) · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the exploration for potential inhibitors of HIV has been increased due to the development of drug resistant HIV strains in infected people undergoing antiretroviral agents treatment. In this report, we studied the anti-HIV properties of ethyl gallate (EG) against a panel of HIV-1 strains in in vitro conditions. Different clinical isolates and laboratory strains of HIV-1 were tested for their sensitivity with EG. We found that EG exhibited non-toxic nature over a wide range of cell lines from different tissue origin. Serum proteins have little to no impact on the antiviral activity of EG. In the present study, EG was found to be a promising anti-HIV agent.

Indexed as

Anti-HIVCytotoxicityEthyl gallateHIV-1 clinical isolatesSerum shift

Identifiers

PMID32206695
PMCPMC7085494
OpenAlexW2996704958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.