Evidence map›Paper›PMID 32206590›Full record

ReviewTranslational pediatrics2020

Cerebral palsy in children: a clinical overview.

Dilip R Patel, Mekala Neelakantan, Karan Pandher, Joav Merrick

4 registry-linked trialsOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Translational pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 171 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
171citing papers in PubMed, 9 pooled it
33.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04755556 nacompletednot on this map

Effectiveness of Routine Physical Therapy With or Without Home Based Intensive Bimanual Training on Clinical Outcomes in Cerebral Palsy Children: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of LahoreRan2020 to 2020Enrolled30ConditionsCerebral PalsyArmshome based intensive bimanual training, Routine Physical Therapy
NCT04923438 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The Effect of Telerehabilitation on the Quality of Life, Anxiety and Depression Levels of Children With Cerebral Palsy and Their Caregivers

TypeinterventionalSponsorMarmara UniversityRan2021 to 2021Enrolled34ConditionsCerebral PalsyArmsTelerehabilitation, Control
NCT05134259 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Role of Repetitive Transcranial Magnetic Stimulation in Spastic Hemiplegic Cerebral Palsy in a Sample of Egyptian Children

TypeinterventionalSponsorAl-Azhar UniversityRan2022 to 2022Enrolled60ConditionsCerebral PalsyArmsRepetitive Transcranial Magnetic Stimulation
NCT06673849 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effects of Rhythmic Stabilization Versus Ball Balancing on Upper Extremity Function in Children With Spastic Cerebral Palsy

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2025Enrolled36ConditionsSpastic Cerebral Palsy (sCP)ArmsRhythmic Stabilization, Ball Balancing
3 · Its place in the literature

Who cites it

171 citing papers in PubMed, 9 syntheses or guidelines pooled it, 501 citations in OpenAlex.

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111 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Dilip R PatelDepartment of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kamalazoo, MI, USA.
Mekala NeelakantanDepartment of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kamalazoo, MI, USA.
Karan PandherChicago Medical School at Rosalind Franklin University, Chicago, IL, USA.
Joav MerrickHadassah Hebrew University Medical Center, Jarusalem, Israel.
Hadassah Medical Center · ILRosalind Franklin University of Medicine and Science · USStryker (United States) · USWestern Michigan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral palsy (CP) is a disorder characterized by abnormal tone, posture and movement and clinically classified based on the predominant motor syndrome-spastic hemiplegia, spastic diplegia, spastic quadriplegia, and extrapyramidal or dyskinetic. The incidence of CP is 2-3 per 1,000 live births. Prematurity and low birthweight are important risk factors for CP; however, multiple other factors have been associated with an increased risk for CP, including maternal infections, and multiple gestation. In most cases of CP the initial injury to the brain occurs during early fetal brain development; intracerebral hemorrhage and periventricular leukomalacia are the main pathologic findings found in preterm infants who develop CP. The diagnosis of CP is primarily based on clinical findings. Early diagnosis is possible based on a combination of clinical history, use of standardized neuromotor assessment and findings on magnetic resonance imaging (MRI); however, in most clinical settings CP is more reliably recognized by 2 years of age. MRI scan is indicated to delineate the extent of brain lesions and to identify congenital brain malformations. Genetic tests and tests for inborn errors of metabolism are indicated based on clinical findings to identify specific disorders. Because CP is associated with multiple associated and secondary medical conditions, its management requires a multidisciplinary team approach. Most children with CP grow up to be productive adults.

Indexed as

Cerebral palsy (CP)extrapyramidalphysiotherapyspastic diplegiaspastic hemiplegiaspasticityspastic quadriplegia

Identifiers

PMID32206590
PMCPMC7082248
OpenAlexW3003406845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.