Evidence map›Paper›PMID 32206584›Full record

ReviewTranslational pediatrics2020

Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation.

Holly Hodges, Casey Fealko, Neelkamal Soares

3 registry-linked trialsOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Translational pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 421 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
421citing papers in PubMed, 11 pooled it
44.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05868720 naunknown statusnot on this mapstarted 2023, after this paper: background citation

EFFECT OF RISPERIDONE vs ARIPIPRAZOLE ON OXIDATIVE STRESS IN PATIENTS WITH AUTISM SPECTRUM DISORDER: A RANDOMIZED CONTROLLED TRIAL

TypeinterventionalSponsorAll India Institute of Medical Sciences, BhubaneswarRan2023 to 2025Enrolled42ConditionsThe Goal of This Trial is to to Compare the Effect of Risperidone vs Aripiprazole in Terms of Change in Serum Glutathione LevelArmsRisperidone, Aripiprazole
NCT06805916 naenrolling by invitationnot on this mapstarted 2023, after this paper: background citation

Promoting Communicative Initiative in Minimally Verbal Autistic Children Through Interaction with the Humanoid Social Robot

TypeinterventionalSponsorIRCCS Centro Neurolesi Bonino PulejoRan2023 to 2025Enrolled100ConditionsAutism Spectrum DisorderArmsNAO-Assisted Therapy, Standard therapeutic
NCT07068659 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Circuit Aerobic Training and Circuit Resistance Training on Cardiorespiratory Fitness, Cardiovascular Response, and Peak Expiratory Flow Rate in Autistic Spectrum Disorder Children

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled32ConditionsAutismArmsCircuit Aerobic Training, Circuit Resistance Training
3 · Its place in the literature

Who cites it

421 citing papers in PubMed, 11 syntheses or guidelines pooled it, 988 citations in OpenAlex.

  1. Pooled it
  2. Delayed Diagnosis of Autism Spectrum Disorder in Adolescent Boys.Advances in experimental medicine and biology · 2026
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361 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Holly HodgesDepartment of Pediatrics, Baylor College of Medicine and Meyer Center for Developmental Pediatrics, Texas Children's Hospital, Houston, TX, USA.
Casey FealkoWestern Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.
Neelkamal SoaresDepartment of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, Kalamazoo, MI, USA.
Stryker (United States) · USTexas Children's Hospital · USWestern Michigan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and the presence of restricted interests and repetitive behaviors. There have been recent concerns about increased prevalence, and this article seeks to elaborate on factors that may influence prevalence rates, including recent changes to the diagnostic criteria. The authors review evidence that ASD is a neurobiological disorder influenced by both genetic and environmental factors affecting the developing brain, and enumerate factors that correlate with ASD risk. Finally, the article describes how clinical evaluation begins with developmental screening, followed by referral for a definitive diagnosis, and provides guidance on screening for comorbid conditions.

Indexed as

Autism spectrum disorder (ASD)etiologyevaluationmedical comorbidityprevalencescreening

Identifiers

PMID32206584
PMCPMC7082249
OpenAlexW2981275956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.