ArticleBiomedical optics express2020
Colorimetrical uncertainty of a hyperspectral imaging microscopy system for assessing whole-slide imaging devices.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
- Medical hyperspectral imaging: an updated review of technology advancements and biomedical applications.Journal of biomedical optics · 2026Pooled it
- Colorimetrical uncertainty estimation for the performance assessment of whole slide imaging scanners.Journal of medical imaging (Bellingham, Wash.) · 2021Article
- Reproducible Color Gamut of Hematoxylin and Eosin Stained Images in Standard Color Spaces.Journal of pathology informatics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A whole-slide imaging (WSI) device is a color medical imaging system whose application in digital pathology is to digitalize stained tissue samples into electronic images for pathologists to diagnose without using a conventional light microscope. Testing the color performance of a WSI device usually implies a color target with known truth that is compared with the device output to estimate color differences. Using stained tissue samples as color targets is challenging because the cellular features cannot be measured with ordinary spectroradiometers unless a hyperspectral imaging microscopy system (HIMS) is used. The goal of this study is to determine the colorimetrical uncertainty of such a reference HIMS that is designed to assess the color performance of WSI devices. A set of optical filters are used for that purpose. The color truth, in terms of spectral transmittance in the visible band, of the optical filters is measured by a reference spectroradiometer. The spectral transmittance is combined with a standard illuminant to generate colorimetrical measures using the CIEXYZ and CIELAB formulas. The differences between the reference HIMS and the reference spectroradiometer are evaluated using the CIE 1976 color difference formulas.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.