ArticleBiomedical optics express2020
Quantitative phase imaging of stromal prognostic markers in pancreatic ductal adenocarcinoma.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 30 citations in OpenAlex.
- Whole-slide mapping of tumor tissue fiber architecture via computational scattered light imaging.Biomedical optics express · 2026Article
- Quantitative phase imaging techniques for measuring scattering properties of cells and tissues: a review-part II.Journal of biomedical optics · 2024Review
- Quantitative phase imaging techniques for measuring scattering properties of cells and tissues: a review-part I.Journal of biomedical optics · 2024Review
- Panoramic quantitative phase imaging of adherent live cells in a microfluidic environment.Biomedical optics express · 2023Article
- Synthetic aperture interference light (SAIL) microscopy for high-throughput label-free imaging.Applied physics letters · 2021Article
- Label-free SARS-CoV-2 detection and classification using phase imaging with computational specificity.Light, science & applications · 2021Article
- Monitoring reactivation of latent HIV by label-free gradient light interference microscopy.iScience · 2021Article
- Spatial light interference microscopy: principle and applications to biomedicine.Advances in optics and photonics · 2021Article
- Computational interference microscopy enabled by deep learning.APL photonics · 2021Article
- Fabrication and Bonding of Refractive Index Matched Microfluidics for Precise Measurements of Cell Mass.Polymers · 2021Article
- Navigating the Collagen Jungle: The Biomedical Potential of Fiber Organization in Cancer.Bioengineering (Basel, Switzerland) · 2021Review
- High spatially sensitive quantitative phase imaging assisted with deep neural network for classification of human spermatozoa under stressed condition.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
New quantitative prognostic markers are needed for improved pancreatic ductal adenocarcinoma (PDAC) prognosis. Second harmonic generation microscopy has been used to show that collagen fiber alignment in PDAC is a negative prognostic factor. In this work, a series of PDAC and normal adjacent tissue (NAT) biopsies were imaged with spatial light interference microscopy (SLIM). Quantitative analysis performed on the biopsy SLIM images show that PDAC fiber structures have lower alignment per unit length, narrower width, and are longer than NAT controls. Importantly, fibrillar collagen in PDAC shows an inverse relationship between survival data and fiber width and length (p < 0.05).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.