ArticleBiomedical optics express2020
Cost-efficient open source laser engine for microscopy.
Article in Biomedical optics express, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Fluorescence-lifetime optical electrophysiology in contracting cardiomyocytes.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Rapid spectral shaping for time domain and swept source full field OCT.Biomedical optics express · 2025Article
- Fourier synthesis optical diffraction tomography for kilohertz rate volumetric imaging.Science advances · 2025Article
- Approaching maximum resolution in structured illumination microscopy via accurate noise modeling.Npj imaging · 2025Article
- Real-time wide-field fluorescence lifetime imaging via single-snapshot acquisition for biomedical applications.PhotoniX · 2025Article
- A Rapid Nanofocusing Method for a Deep-Sea Gene Sequencing Microscope Based on Critical Illumination.Sensors (Basel, Switzerland) · 2024Article
- Approaching Maximum Resolution in Structured Illumination Microscopy via Accurate Noise Modeling.bioRxiv : the preprint server for biology · 2024Article
- Article
- Skp1 proteins are structural components of the synaptonemal complex inScience advances · 2024Article
- Simple, Economic, and Robust Rail-Based Setup for Super-Resolution Localization Microscopy.The journal of physical chemistry. A · 2023Article
- Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging.Nature methods · 2023Article
- The K2: Open-source simultaneous triple-color TIRF microscope for live-cell and single-molecule imaging.HardwareX · 2023Article
- MicroFPGA: An affordable FPGA platform for microscope control.HardwareX · 2023Article
- Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging.Nature protocols · 2022Review
- Article
- Open microscopy in the life sciences: quo vadis?Nature methods · 2022Article
- Understanding immune signaling using advanced imaging techniques.Biochemical Society transactions · 2022Review
- An economic, square-shaped flat-field illumination module for TIRF-based super-resolution microscopy.Biophysical reports · 2022Article
- Direct supercritical angle localization microscopy for nanometer 3D superresolution.Nature communications · 2021Article
- EMU: reconfigurable graphical user interfaces for Micro-Manager.BMC bioinformatics · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Scientific-grade lasers are costly components of modern microscopes. For high-power applications, such as single-molecule localization microscopy, their price can become prohibitive. Here, we present an open-source high-power laser engine that can be built for a fraction of the cost. It uses affordable, yet powerful laser diodes at wavelengths of 405 nm, 488 nm and 638 nm and optionally a 561 nm diode-pumped solid-state laser. The light is delivered to the microscope via an agitated multimode fiber in order to suppress speckles. We provide the parts list, CAD files and detailed descriptions, allowing any research group to build their own laser engine.
Identifiers
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Registered trials
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