Evidence map›Paper›PMID 32206344›Full record

ArticleActa radiologica open2020

Can iterative reconstruction algorithms replace tube loading compensation in low kVp hepatic CT? Subjective versus objective image quality.

Fredrik Holmquist, Marcus Söderberg, Ulf Nyman, Tobias Fält, Roger Siemund, Mats Geijer

Open access · goldAbstract read
In one paragraph

Article in Acta radiologica open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fredrik HolmquistDepartment of Medical Imaging and Physiology, Skåne University Hospital, Lund University, Lund, Sweden.ORCID https://orcid.org/0000-0002-4123-145X
Marcus SöderbergMedical Radiation Physics, Department of Translational Medicine, Skåne University Hospital, Lund University, Malmö, Sweden.
Ulf NymanDepartment of Translational Medicine, Division of Medical Radiology, Skåne University Hospital, Lund University, Malmö, Sweden.
Tobias FältDepartment of Translational Medicine, Division of Medical Radiology, Skåne University Hospital, Lund University, Malmö, Sweden.
Roger SiemundDepartment of Medical Imaging and Physiology, Skåne University Hospital, Lund University, Lund, Sweden.
Mats GeijerDepartment of Medical Imaging and Physiology, Skåne University Hospital, Lund University, Lund, Sweden.
Lund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatic computed tomography (CT) with decreased peak kilovoltage (kVp) may be used to reduce contrast medium doses in patients at risk of contrast-induced acute kidney injury (CI-AKI); however, it increases image noise. To preserve image quality, noise has been controlled by X-ray tube loading (mAs) compensation (TLC), i.e. increased mAs. Another option to control image noise would be to use iterative reconstructions (IR) algorithms without TLC (No-TLC). It is unclear whether this may preserve image quality or only reduce image noise. PURPOSE: To evaluate image quality of 80 kVp hepatic CT with TLC and filtered back projection (FBP) compared with 80 kVp with No-TLC and IR algorithms (SAFIRE 3 and 5) in patients with eGFR <45 mL/min. MATERIAL AND

methodsForty patients (BMI 18-32 kg/m

resultsComparing TLC/FBP with No-TLC/IR-S5, there were no significant differences regarding hepatic attenuation, image noise, enhancement, SNR and CNR: 114 vs. 115 HU, 14 vs. 14 HU, 55 vs. 57 HU, 8.0 vs. 8.4, and 3.8 vs. 4.0 in median, respectively. No-TLC/IR-S3 resulted in higher image noise and lower SNR and CNR than TLC/FBP. Subjective image quality scoring with visual grading showed statistically significantly inferior scores for IR-S5 images.

conclusionCT of 80 kVp to reduce contrast medium dose in patients at risk of CI-AKI combined with IR algorithms with unchanged tube loading to control image noise does not provide sufficient diagnostic quality.

Indexed as

acute kidney injuryComputed tomographycontrast mediafiltered back-projectionimage noiseliverlow tube voltage

Identifiers

PMID32206344
PMCPMC7076580
OpenAlexW3012556124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.