Evidence map›Paper›PMID 32206320›Full record

ArticleNeuro-oncology practice2020

Fraser Henderson, Steven Brem, Donald M O'Rourke, MacLean Nasrallah, Vivek P Buch, Anthony J Young, Robert K Doot, Austin Pantel, Arati Desai, Stephen J Bagley and 1 more

2 registry-linked trialsOpen access · bronzeAbstract readCase Reports
In one paragraph

Article in Neuro-oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05553041 early_phase1recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of 18F-Fluciclovine PET-MRI to Differentiate Tumor Progression From Post-treatment Changes in Pediatric High-grade Glioma (HGG)

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2024 to 2027Enrolled30ConditionsGlioma, High Grade Glioma, Glioma, Malignant, Glioma IntracranialArms18F-Fluciclovine PET-MRI
NCT05555550 early_phase1recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2026 to 2027Enrolled30ConditionsGlioma, Low-grade Glioma, Low Grade Glioma of Brain, Glioma, MalignantArms18F-Fluciclovine
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Clinical Practice Guidelines forAnnals of nuclear medicine · 2025
    Guideline
  2. Article
  3. Metabolic Imaging and Molecular Signatures Reveal Metabolic Phenotypes in Recurrent Glioblastoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  4. Article
  5. Review
  6. Journal of neuro-oncology · 2023
    Article
  7. Review
  8. PET/MRI in Pediatric Neuroimaging: Primer for Clinical Practice.AJNR. American journal of neuroradiology · 2022
    Review
  9. Article
  10. Neuro-oncology practice · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Fraser HendersonDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia.ORCID 0000-0003-2253-7506
Steven BremDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia.
Donald M O'RourkeDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia.
MacLean NasrallahDepartment of Pathology, Hospital of the University of Pennsylvania, Philadelphia.
Vivek P BuchDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia.
Anthony J YoungDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia.
Robert K DootDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia.
Austin PantelDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia.
Arati DesaiDivision of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia.
Stephen J BagleyDivision of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia.
S Ali NabavizadehDepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia.
Hospital of the University of Pennsylvania · USMedical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differentiation of true tumor progression from treatment-related effects remains a major unmet need in caring for patients with glioblastoma. Here, we report how the intraoperative combination of MRI with

Indexed as

18F-fluciclovineglioblastomapositron emission tomography (PET)pseudoprogression

Identifiers

PMID32206320
PMCPMC7081387
OpenAlexW2996481229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.