SynthesisOpen heart2020
Isolated surgical tricuspid repair versus replacement: meta-analysis of 15 069 patients.
Synthesis in Open heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Navigating isolated tricuspid regurgitation: A practical guide to perioperative and periprocedural management.JTCVS open · 2026Article
- High Efficacy and Low Early Mortality in High-Volume Center Tricuspid Valve Surgery.The Thoracic and cardiovascular surgeon · 2026Article
- The In-Situ Mechanics of the Tricuspid Valve: Strain Heterogeneity and Anisotropy via 3D Digital Image Correlation.Experimental mechanics · 2026Article
- Long-term outcomes of isolated tricuspid surgery in 3706 patients: Implications for the future.The Journal of thoracic and cardiovascular surgery · 2025Article
- Transcatheter tricuspid valve intervention versus optimal medical therapy alone for severe tricuspid regurgitation: an updated meta-analysis with reconstructed time-to-event data.International journal of cardiology. Heart & vasculature · 2025Article
- Isolated Tricuspid Regurgitation: When Is Surgery Appropriate? A State-of-the-Art Narrative Review.Journal of clinical medicine · 2025Review
- Efficacy and Safety of Transcatheter Tricuspid Valve Replacement in Patients With Moderate to Severe Tricuspid Regurgitation: A Systematic Review and Meta-Analysis on Clinical Outcomes and Echocardiographic Indices.Health science reports · 2025Review
- Outcomes of isolated tricuspid replacement versus repair among older patients with tricuspid regurgitation in the United States.JTCVS open · 2025Article
- Pacemaker Implantation After Tricuspid Valve Surgery at a High-Volume Regional Reference Center.Annals of thoracic surgery short reports · 2024Article
- Tricuspid valve surgery for acute infective endocarditis can be performed with very low operative mortality.JTCVS open · 2024Article
- Early and mid-term outcomes of tricuspid valve surgery in patients with functional tricuspid regurgitation induced by atrial fibrillation.Journal of thoracic disease · 2024Article
- Incidence, Risk Factors, and Outcomes Associated With Permanent Pacemaker Implantation Following Tricuspid Valve Surgery.Journal of the American Heart Association · 2024Article
- Tricuspid valve disease and cardiac implantable electronic devices.European heart journal · 2024Review
- Isolated Tricuspid Operations: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis.The Annals of thoracic surgery · 2023Article
- Minimal Access Tricuspid Valve Surgery.Journal of cardiovascular development and disease · 2023Review
- Examining the forgotten valve: outcomes of tricuspid valve surgery, a 15-year experience.Irish journal of medical science · 2022Article
- Commentary: Bespoke tricuspid tailoring-bringing patient-specific valve repair to the forgotten valve.JTCVS techniques · 2021Article
- Tricuspid valve repair in isolated tricuspid pathology: a 12-year single center experience.Journal of cardiothoracic surgery · 2020Article
- Isolated tricuspid valve surgery after congenital versus left heart-disease surgery: mid-term outcomes.Journal of thoracic disease · 2020Article
- Stubbornly preserving native leaflets is not always right: a case of tricuspid valve re-operation.Cardiovascular journal of AfricaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Tricuspid valve disease is increasingly encountered, but surgery is rarely performed in isolation, in part because of a reported higher operative risk than other single-valve operations. Although guidelines recommend valve repair, there is sparse literature for the optimal surgical approach in isolated tricuspid valve disease. We performed a meta-analysis examining outcomes of isolated tricuspid valve repair versus replacement. Methods: We searched Pubmed, Embase, Scopus and Cochrane from January 1980 to June 2019 for studies reporting outcomes of both isolated tricuspid valve repair and replacement, excluding congenital tricuspid aetiologies. Data were extracted and pooled using random-effects models and Review Manager 5.3 software. Results: There were 811 article abstracts screened, from which 52 full-text articles reviewed and 16 studies included, totalling 6808 repairs and 8261 replacements. Mean age ranged from 36 to 68 years and females made up 24%-92% of these studies. Pooled operative mortality rates and odds ratios (95% confidence intervals) for isolated tricuspid repair and replacement surgery were 8.4% vs 9.9%, 0.80 (0.64 to 1.00). Tricuspid repair was also associated with lower in-hospital acute renal failure 12.4% vs 15.6%, 0.82 (0.72 to 0.93) and pacemaker implantation 9.4% vs 21.0%, 0.37 (0.24 to 0.58), but higher stroke rate 1.5% vs 0.9%, 1.63 (1.10 to 2.41). There were no differences in rates of prolonged ventilation, mediastinitis, return to operating room or late mortality. Conclusion: Isolated tricuspid valve repair was associated with significantly reduced in-hospital mortality, renal failure and pacemaker implantation compared with replacement and is therefore recommended where feasible for isolated tricuspid valve disease, although its higher stroke rate warrants further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.