Evidence map›Paper›PMID 32206258›Full record

ArticleChemical science2019

Structural analysis and cellular visualization of APP RNA G-quadruplex.

Kaixin Lyu, Shuo-Bin Chen, Chun-Yin Chan, Jia-Heng Tan, Chun Kit Kwok

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Profiling RNA G-Quadruplexes In vivo.Current protocols · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Crosstalk between G-quadruplex and ROS.Cell death & disease · 2023
    Review
  12. Aptamers as Functional Modules for DNA Nanostructures.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. Recent advances in RNA structurome.Science China. Life sciences · 2022
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kaixin LyuDepartment of Chemistry , City University of Hong Kong , Kowloon Tong , Hong Kong SAR , China . Email: ckkwok42@cityu.edu.hk.ORCID 0000-0002-9330-1296
Shuo-Bin ChenSchool of Pharmaceutical Sciences , Guangdong Provincial Key Laboratory of New Drug Design and Evaluation , Sun Yat-sen University , Guangzhou , 510006 China . Email: tanjiah@mail.sysu.edu.cn.ORCID 0000-0001-9118-2185
Chun-Yin ChanDepartment of Chemistry , City University of Hong Kong , Kowloon Tong , Hong Kong SAR , China . Email: ckkwok42@cityu.edu.hk.ORCID 0000-0003-1745-9742
Jia-Heng TanSchool of Pharmaceutical Sciences , Guangdong Provincial Key Laboratory of New Drug Design and Evaluation , Sun Yat-sen University , Guangzhou , 510006 China . Email: tanjiah@mail.sysu.edu.cn.ORCID 0000-0002-1612-7482
Chun Kit KwokDepartment of Chemistry , City University of Hong Kong , Kowloon Tong , Hong Kong SAR , China . Email: ckkwok42@cityu.edu.hk.ORCID 0000-0001-9175-8543
City University of Hong Kong · HKSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA G-quadruplexes (rG4s) are emerging structural motifs that are of pivotal importance in chemistry and biology; however, the current structural information of rG4s is limited, with their folding status and functions in cells remaining elusive. Here, we develop and employ a multi-disciplinary approach to characterize the structure, formation and function of an individual rG4 of interest

Identifiers

PMID32206258
PMCPMC7069244
OpenAlexW2982414202

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.