Evidence map›Paper›PMID 32206219›Full record

ArticleAddiction & health2019

Correlation among the Behavioral Features in the Offspring of Morphine-Abstinent Rats.

Hamid Ahmadian-Moghadam, Ardeshir Akbarabadi, Heidar Toolee, Mitra Sadat Sadat-Shirazi, Solmaz Khalifeh, Saba Niknamfar, Mohammad Reza Zarrindast

Open access · greenAbstract read
In one paragraph

Article in Addiction & health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hamid Ahmadian-MoghadamIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Ardeshir AkbarabadiIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Heidar TooleeDepartment of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mitra Sadat Sadat-ShiraziIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Solmaz KhalifehCognitive and Neuroscience Research Center, Amir Al-Momenin Hospital, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Saba NiknamfarIranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza ZarrindastIranian National Center for Addiction Studies AND Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCritical analysis of new evidence in medical sciences relies on statistics in terms of correlation. The aim of the present study was to evaluate the correlation coefficients among the behavioral features in the offspring of morphine-abstinent parent(s).

methodsThe offspring of rats with various parental morphine-exposure were divided into four groups including offspring with healthy parents (CTL), offspring with paternal morphine-abstinent (PMA) parent, offspring with maternal morphine-abstinent (MMA) parent, and offspring with both morphine-abstinent (BMA) parents. Pain perception, depression-like behavior and avoidance-memory in the offspring were quantified. The association between variables was measured using Pearson correlation analysis.

findingsA strong correlation was observed between pain and depressive-like behavior in female and male offspring of healthy parents. Moreover, in the male and female offspring of healthy parents and BMA, no significant correlation was observed between avoidance memory and pain behavior or depressive-like behavior. However, in the offspring of MMA, a strong correlation was observed between avoidance memory and depressive-like behavior.

conclusionThe results revealed that in comparison with the offspring with CTL, the correlation among the behavioral futures in the offspring with MMA or PMA parents is significantly different.

Indexed as

AdministrationBehaviorCorrelation of dataEpigenomicsMorphineOral

Identifiers

PMID32206219
PMCPMC7073814
OpenAlexW3016961633

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.