Evidence map›Paper›PMID 32206111›Full record

Trial reportTheranostics2020

Differentiation of benign and malignant lymph nodes in pediatric patients on ferumoxytol-enhanced PET/MRI.

Anne Monika Muehe, Florian Siedek, Ashok Joseph Theruvath, Jayne Seekins, Sheri L Spunt, Allison Pribnow, Florette Kimberly Hazard, Tie Liang, Heike Daldrup-Link

Open access · goldAbstract readClinical TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 33 citations in OpenAlex.

  1. Trial
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  5. Identifying Castleman disease from non-clonal inflammatory causes of generalized lymphadenopathy.Hematology. American Society of Hematology. Education Program · 2024
    Review
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  15. Diagnostic Accuracy of 2-[European radiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Anne Monika MueheDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA.
Florian SiedekDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA.
Ashok Joseph TheruvathDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA.
Jayne SeekinsDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA.
Sheri L SpuntDepartment of Pediatrics, Division of Hematology and Oncology, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Allison PribnowDepartment of Pediatrics, Division of Hematology and Oncology, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Florette Kimberly HazardDepartment of Pathology, Division of Hematology and Oncology, Lucile Packard Children's Hospital, Stanford University, Stanford, CA, USA.
Tie LiangDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA.
Heike Daldrup-LinkDepartment of Radiology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA, USA.
Stanford University · US

Funding

Personalized Whole Body Staging for Children with Cancer: A Solution to the Conundrum of Long-Term Side Effects from CT and PET/CT ScansR01HD081123 · NICHD · STANFORD UNIVERSITY · PI DALDRUP-LINK, HEIKE ELIZABETH · 2015 to 2019
$2.5M
NICHD NIH HHS R01 HD081123
6 · The paper itself

Abstract

The composition of lymph nodes in pediatric patients is different from that in adults. Most notably, normal lymph nodes in children contain less macrophages. Therefore, previously described biodistributions of iron oxide nanoparticles in benign and malignant lymph nodes of adult patients may not apply to children. The purpose of our study was to evaluate if the iron supplement ferumoxytol improves the differentiation of benign and malignant lymph nodes in pediatric cancer patients on

Indexed as

AdolescentCell DifferentiationChildFemaleFerrosoferric OxideFluorodeoxyglucose F18HumansLymph NodesMagnetic Resonance ImagingMaleNanoparticlesNeoplasmsPositron-Emission TomographyProspective StudiesRadiopharmaceuticalsFerrosoferric OxideFluorodeoxyglucose F18Radiopharmaceuticalscancer imagingferumoxytollymph nodesnanoparticlesPET/MRI

Identifiers

PMID32206111
PMCPMC7069081
OpenAlexW3007219440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.