ArticleARYA atherosclerosis2019
Water hardness zoning of Isfahan Province, Iran, and its relationship with cardiovascular mortality, 2013-2015.
Article in ARYA atherosclerosis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- Healthy eating behaviors may be associated with lower risk of premature coronary artery disease: A multi-center case-control study.Journal of health, population, and nutrition · 2025Article
- Evaluation of the Relationship Between Water Hardness and Incidence of Cardiovascular Diseases in Mashhad, Iran During 2018-2020: A Cross-Sectional Study.Health science reports · 2025Article
- Assessment of short-term results of thrombosuction during primary percutaneous coronary intervention in patients with acute myocardial infarction.Future cardiology · 2024Article
- The Relationship between Mortality from Cardiovascular Diseases and Total Drinking Water Hardness: Systematic Review with Meta-Analysis.Foods (Basel, Switzerland) · 2023Review
- Electrolyte-Gated Graphene Field Effect Transistor-Based CaSensors (Basel, Switzerland) · 2022Article
- Water Quality and Mortality from Coronary Artery Disease in Sardinia: A Geospatial Analysis.Nutrients · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular disease (CVD) is one of the common diseases and today, it is considered as not only an important cause of mortality but also a significant aspect of health geography. The evidence presented in the literature indicates that hard water may reduce the cases of sudden death caused by CVDs because drinking water contains significant amounts of calcium and magnesium, which play a crucial role in the electrical activity of heart. Hence, the present study aimed at investigating the relationship between water hardness and CVD mortality rate in Isfahan, Iran.
methodsIn this ecological study, the available data regarding the cardiovascular mortality rate and water hardness have been used. Preparation of zoning map has been conducted using the Geographic Information System (GIS) software considering Inverse Distance Weighting (IDW) interpolation models. Moreover, statistical analysis has been conducted using SPSS software.
resultsA reverse relationship was observed between cardiovascular mortality rate and water hardness. However, the observed relationship was not statistically significant (2013: r = -0.066, 2014: r = -0.155, 2015: r = -0.051, P > 0.050).
conclusionThe results of mapping with GIS and statistical analysis with SPSS both indicated a non-significant inverse relationship between the water hardness and CVDs. However, lack of a significant relationship highlights the necessity of conducting similar studies involving larger sample sizes and wider areas of investigation to present a definitive and generalizable result.
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