Evidence map›Paper›PMID 32206047›Full record

ArticleDose-response : a publication of International Hormesis Society

Biphasic Dose-Response Induced by PCB150 and PCB180 in HeLa Cells and Potential Molecular Mechanisms.

Ainy Zehra, Muhammad Zaffar Hashmi, Abdul Majid Khan, Tariq Malik, Zaigham Abbas

Open access · goldAbstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Ainy ZehraDepartment of Zoology, University of Punjab, Lahore, Pakistan.
Muhammad Zaffar HashmiDepartment of Chemistry, COMSATS University Islamabad, Pakistan.ORCID https://orcid.org/0000-0003-1385-5326
Abdul Majid KhanDepartment of Zoology, University of Punjab, Lahore, Pakistan.
Tariq MalikDepartment of Pharmacy, Islamia University Bahawalpur, Pakistan.
Zaigham AbbasMinistry of Climate Change, Islamabad, Pakistan.
University of the Punjab · PKCOMSATS University Islamabad · PKGovernment of Pakistan · PKIslamia University of Bahawalpur · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The polychlorinated biphenyls (PCBs) are persistent and their dose-dependent toxicities studies are not well-established. In this study, cytotoxic and genotoxic effects of PCB150 and PCB180 in HeLa cells were studied. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay indicated that the cell proliferation was stimulated at low doses (10

Indexed as

antioxidant enzymesHeLa cellshormesisMAPKsoxidative stressPCBs

Identifiers

PMID32206047
PMCPMC7076582
OpenAlexW3011621803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.