Evidence map›Paper›PMID 32206045›Full record

ArticleJournal of interventional cardiology2020

Optimal Timing of Invasive Coronary Angiography following NSTEMI.

Thabo Mahendiran, David Nanchen, David Meier, Baris Gencer, Roland Klingenberg, Lorenz Räber, David Carballo, Christian M Matter, Thomas F Lüscher, Stephan Windecker and 4 more

Abstract read
In one paragraph

Article in Journal of interventional cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Occlusion myocardial infarction in type I NSTEMI: prevalence, characteristics, management, and long-term outcome.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  2. Article
  3. Article
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  5. Timing of coronary angiography in patients with non-ST-elevation acute coronary syndrome: long-term clinical outcomes from the nationwide SWEDEHEART registry.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thabo MahendiranDepartment of Cardiology, Lausanne University Center Hospital, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-0025-8162
David NanchenCenter for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
David MeierDepartment of Cardiology, Lausanne University Center Hospital, Lausanne, Switzerland.
Baris GencerDepartment of Cardiology, Geneva University Hospitals, Geneva, Switzerland.
Roland KlingenbergDepartment of Cardiology, Kerckhoff Klinik, Bad Nauheim, Germany.
Lorenz RäberDepartment of Cardiology, University Hospital of Zurich, Zurich, Switzerland.
David CarballoDepartment of Cardiology, Geneva University Hospitals, Geneva, Switzerland.
Christian M MatterDepartment of Cardiology, University Hospital of Zurich, Zurich, Switzerland.
Thomas F LüscherCenter for Molecular Cardiology, University of Zurich, Zurich, Switzerland.
Stephan WindeckerDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
François MachDepartment of Cardiology, Geneva University Hospitals, Geneva, Switzerland.ORCID https://orcid.org/0000-0003-3178-9131
Nicolas RodondiDepartment of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Olivier MullerDepartment of Cardiology, Lausanne University Center Hospital, Lausanne, Switzerland.
Stephane FournierDepartment of Cardiology, Lausanne University Center Hospital, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-9422-9521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo obtain a real-world perspective of the optimal timing of angiography performed within 24 hours of admission with non-ST elevation myocardial infarction (NSTEMI).

backgroundCurrent guidelines recommend angiography within 24 hours of hospitalisation with NSTEMI. The recent VERDICT trial found that angiography within 12 hours of admission with NSTEMI was associated with improved cardiovascular outcomes among high-risk patients. We compared the outcomes of real-world NSTEMI patients undergoing angiography within 12 hours of admission with those of patients undergoing angiography 12 to 24 hours after admission.

methodsNSTEMI patients without life-threatening features who received angiography within 24 hours of admission were obtained from the SPUM-ACS registry, a cohort of consecutive patients admitted with acute coronary syndromes to four university hospitals in Switzerland. Cox models assessed for an association between door-to-catheter time and one-year major adverse cardiovascular events (MACE: cardiovascular mortality, myocardial infarction, and stroke).

resultsOf 2672 NSTEMI patients, 1832 met the inclusion criteria. Among them, 1464 patients underwent angiography within 12 hours (12 h group) compared with 368 patients between 12 and 24 hours (12-24 h group). Multiple logistic regression identified out-of-hours admission as the only factor associated with delayed angiography. After 2 : 1 propensity score matching, 736 patients from the 12 h group and 368 patients from the 12-24 h group demonstrated no significant difference in rates of one-year MACE (7.7% vs. 7.3%, HR: 1.050, 95% CI 0.637-1.733,

conclusionsIn an unselected real-world cohort of NSTEMI patients, angiography within 12 hours of admission was not associated with improved one-year cardiovascular outcomes when compared with angiography 12 and 24 hours after admission, even among high-risk patients.

Indexed as

Cardiac CatheterizationCoronary AngiographyNon-ST Elevated Myocardial InfarctionAgedFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CareProportional Hazards ModelsRisk AdjustmentSwitzerlandTime-to-Treatment

Identifiers

PMID32206045
PMCPMC7073472

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.