Evidence map›Paper›PMID 32205581›Full record

ReviewCurrent opinion in nephrology and hypertension2020

Artificial intelligence driven next-generation renal histomorphometry.

Briana A Santo, Avi Z Rosenberg, Pinaki Sarder

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in nephrology and hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Artificial intelligence: is there a potential role in nephropathology?Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
    Article
  8. Article
  9. Multi-Task Learning-Based Immunofluorescence Classification of Kidney Disease.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. AI applications in renal pathology.Kidney international · 2021
    Review
  12. Review
  13. User friendly, cloud based, whole slide image segmentation.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Briana A SantoDepartment of Pathology and Anatomical Sciences, The State University of New York, Buffalo, New York Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Avi Z Rosenberg
Pinaki Sarder
University at Buffalo, State University of New York · USJohns Hopkins University · US

Funding

Coordinating and Bioinformatics Unit for the MMPC/DiaCompU24DK076169 · NIDDK · AUGUSTA UNIVERSITY · PI MCINDOE, RICHARD A. · 2006 to 2018
$42.4M
ConProject-002U2CDK114886 · NIDDK · UNIVERSITY OF WASHINGTON · PI HIMMELFARB, JONATHAN, IYENGAR, SRINIVAS RAVI V · 2017 to 2021
$21.0M
Chronic Kidney Disease (CKD) Biomarkers Consortium Data Coordinating CenterU01DK103225 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SCHRAUBEN, SARAH JEANNE · 2014 to 2020
$5.5M
Computational Imaging of Renal Structures for Diagnosing DiabeticNephropathyR01DK114485 · NIDDK · UNIVERSITY OF FLORIDA · PI Michael Thomas Eadon, Avi Z Rosenberg · 2018 to 2026
$4.7M
NIDDK NIH HHS R01 DK114485NIDDK NIH HHS U01 DK103225NIDDK NIH HHS U24 DK076169NIDDK NIH HHS U2C DK114886
6 · The paper itself

Abstract

purpose of reviewSuccessful integration of artificial intelligence into extant clinical workflows is contingent upon a number of factors including clinician comprehension and interpretation of computer vision. This article discusses how image analysis and machine learning have enabled comprehensive characterization of kidney morphology for development of automated diagnostic and prognostic renal pathology applications. RECENT

findingsThe primordial digital pathology informatics work employed classical image analysis and machine learning to prognosticate renal disease. Although this classical approach demonstrated tremendous potential, subsequent advancements in hardware technology rendered artificial neural networks '(ANNs) the method of choice for machine vision in computational pathology'. Offering rapid and reproducible detection, characterization and classification of kidney morphology, ANNs have facilitated the development of diagnostic and prognostic applications. In addition, modern machine learning with ANNs has revealed novel biomarkers in kidney disease, demonstrating the potential for machine vision to elucidate novel pathologic mechanisms beyond extant clinical knowledge. SUMMARY: Despite the revolutionary developments potentiated by modern machine learning, several challenges remain, including data quality control and curation, image annotation and ontology, integration of multimodal data and interpretation of machine vision or 'opening the black box'. Resolution of these challenges will not only revolutionize diagnostic pathology but also pave the way for precision medicine and integration of artificial intelligence in the process of care.

Indexed as

Artificial IntelligenceMachine LearningHumansImage Processing, Computer-AssistedKidneyNeural Networks, ComputerPrognosis

Identifiers

PMID32205581
PMCPMC7189787
OpenAlexW3012728984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.